Abilify (Aripiprazole)
Class and Category of Drug
Before you buy Abilify (Aripiprazole) online, read common information about the medication.
Chemical class: Dihydrocarbostyril
Therapeutic class: Atypical antipsychotic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Abilify (Aripiprazole) online , you must read how it works.
To treat acute schizophrenia; to maintain stability in patients with schizophrenia
Oral Solution, Orally Disintegrating Tablets, Tablets
Adults. Initial: 10 or 15 mg daily. Increased to 30 mg daily, as needed, with dosage adjustments at 2-wk intervals. Maintenance: 15 mg daily.
To treat acute manic and mixed episodes in bipolar I disorder with or without psychotic features; to maintain stability in patients with bipolar I disorder; as adjunct with lithium or valproate in patients with bipolar I disorder
Oral Solution, Orally Disintegrating Tablets, Tablets
Adults. Initial: 15 mg daily, increased to 30 mg daily, as needed. Maintenance: 15 to 30 mg daily. Maximum: 30 mg daily.
Children ages 10 to 17.Initial: 2 mg daily, increased after 2 days to 5 mg daily and then after 2 days to 10 mg daily. Increased in 5-mg increments, as needed, at 2-wk intervals. Maintenance: Lowest dose possible to maintain remission. Maximum: 30 mg daily.
As adjunct to treat depression in patients already taking an antidepressant
Oral Solution, Orally Disintegrating, Tablets,Tablets
Adults. Initial: 2 to 5 mg daily, with dosage increased to 5 mg daily at 1-wk intervals.
To treat agitation in schizophrenia or bipolar mania
Intramuscular Injection
Adults. Initial: Depending on severity of agitation, 5.25 to 15 mg. May be repeated 2 or more hr later, as needed. Maximum: 30 mg daily.
To treat irritability associated with autistic disorder
Oral Solution, Orally Disintegrating, Tablets,Tablets
Children. Initial: 2 mg daily, with dosage increased after 1 wk to 5 mg daily and then after 1 wk to 10 mg daily and then after 1 wk to 15 mg daily, as needed.
Dosage Adjustment Dosage reduced to half normal amount when given with clarithromycin, fluoxetine, itraconazole, ketoconazole, paroxetine, or quinidine. Dosage doubled when given with carbamazepine.
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Contraindications of Drug
Read contraindications if you want cheap Abilify (Aripiprazole) online.
Breast-feeding, hypersensitivity to aripiprazole or its components
Generic Drug Interactions
Drugs
anticholingerics: Increased risk for potentially fatal elevation of body temperature
carbamazepine and other CYP3A4 inducers: Possibly increased clearance and decreased blood level of aripiprazole
clarithromycin, fluoxetine, paroxetine, quinidine, and other CYP2D6 inhibitors; ketoconazole and other CYP3A4 inhibitors: Possibly inhibited aripiprazole elimination and increased blood level
CNS depressants: Increased CNS depression
Activities
alcohol use: Increased CNS depression
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, agitation, akathisia, anxiety, asthenia, cognitive and motor impairment, confusion, delusions, depression, dizziness, dream disturbances, dystonia, extrapyramidal reactions, fatigue, fever, hallucinations, headache, hostility, insomnia, intracranial hemorrhage, lethargy, light-headedness, mania, nervousness, neuroleptic malignant syndrome, paranoia, restlessness, schizophrenic reaction, seizures, somnolence, stroke (elderly), suicidal ideation, tardive dyskinesia, transient ischemic attack (elderly), tremor
Cardiovascular: Arrhythmias, bradycardia, cardiopulmonary arrest, chest pain, circulatory collapse, deep vein thrombosis, elevated serum CK levels, heart failure, hypertension, MI, orthostatic hypotension, peripheral edema, prolonged QT interval, tachycardia
Eyes, Ears, Nose, And Throat: Blurred vision, conjunctivitis, dry mouth, hepatitis, increased salivation, laryngospasm, nasopharyngitis, oropharyngeal spasm, pharyngitis, rhinitis, sinusitis
Endocrine: Hyperglycemia
Gastrointestinal: Abdominal discomfort, constipation, decreased appetite, diarrhea, difficulty swallowing, gastrointestinal bleeding, indigestion, jaundice, nausea, vomiting
Genitourinary: Renal failure, urinary incontinence
Hematologic: Agranulocytosis, anemia, leukopenia, neutropenia, thrombocytopenia
Musculoskeletal: Arthralgia, elevated blood CK level, muscle spasms, muscleskeletal pain, myalgia, neck and limb rigidity, rhabdomyolysis
Respiratory: Apnea, aspiration, asthma, cough, dyspnea, pneumonia, pulmonary edema or embolism, respiratory failure
Skin: Diaphoresis, dry skin, ecchymosis, pruritus, rash, ulceration, urticaria
Other: Anaphylaxis, angioedema, dehydration, flulike symptoms, heat stroke, weight gain
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Nursing Considerations for Generic Drugs
Aripiprazole shouldn't be used to treat dementia-related psychosis in the elderly because of an increased risk of death.
Use cautiously in patients with CV disease, cerebrovascular disease, or conditions that would predispose them to hypotension.
Also use cautiously in elderly patients because of increased risk of serious adverse cerebrovascular effects, such as stroke and transient ischemic attack.
Oral solution may be given on a milligram-per-milligram basis in place of tablets up to 25 mg. For example, if patient needs 30 mg of tablet and is switched to oral solution, expect to give 25 mg of solution.
Inject parenteral form slowly, deep into the muscle, and never intravenous or subcutaneously
Monitor patient for difficulty swallowing or excessive somnolence, which could predispose to accidental injury or aspiration.
WARNING Aripiprazole rarely may cause neuroleptic malignant syndrome, tardive dyskinesia, and seizures. Monitor patient closely throughout therapy, and take safety precautions as needed.
Monitor patient's blood glucose level routinely; risk of hyperglycemia may increase.
Watch patients closely (especially children, adolescents, and young adults) for suicidal tendencies, particularly when therapy starts and dosage changes, because depression may worsen temporarily during these times.
Monitor patient's CBC, as ordered, because serious adverse hematologic reactions may occur, such as agranulocytosis, leukopenia, and neutropenia. Assess more often during first few months of therapy if patient has a history of drug-induced leukopenia or neutropenia or a significantly low WBC count. If abnormalities occur during therapy, watch for fever or other signs of infection, notify prescriber and, if severre, expect drug to be stopped.
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Aripiprazole
Preparations
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