Adalat (Nifedipine) - Blood Pressure/Cholesterol
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Top » Catalog » Blood Pressure/Cholesterol » Adalat (Nifedipine)


Adalat (Nifedipine)

$51.26


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Adalat (Nifedipine)

Class and Category of Drug

Before you buy Adalat (Nifedipine) online, read common information about the medication.

Chemical class: Dihydropyridine derivative

Therapeutic class: Antianginal, antihypertensive

Pregnancy category: C

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Drug Indications and Dosages

Before purchase Adalat (Nifedipine) online , you must read how it works.

To manage angina

Capsules (Adalat, Apo-Nifed, Novo-nifedin, Nu-Nifed, Procardia)

Adults. Initial: 10 mg t.i.d., increased oveк 1 to 2 wk as needed. Maintenance: 10 to 20 mg t.i.d. Maximum: 180 mg daily, 30 mg/dose.

E.R. Tablets (Adalat XL, Procardia XL)

Adults. Initial: 30 to 60 mg daily, increase or decreased over 7 to 14 days based on patient response. Maximum: 90 mg daily.

To manage hypertension

E.R. Tablets (Adalat CC)

Adults. Initial: 30 mg daily. Maintenance: 30 to 60 mg daily, increased or decrease over 7 to 14 days based on patient response. Maximum: 90 mg daily.

E.R.Tablets (Adalat PA)

Adults. Initial: 10 to 20 mg b.i.d., increased every 3 wk based on patient response. Maintenance: 20 mg b.i.d. Maximum: 80 mg daily.

E.R. Tablets (Adalat XL)

Adults. Initial: 30 to 60 mg daily, increased or decreased over 7 to 14 days based on patient response. Maintenance: 60 to 90 mg daily. Maximum: 120 mg daily.

E.R.Tablets (Procardia XL)

Adults. 30 to 60 mg daily, increased or decreased over 7 to 14 days based on patient response. Maximum: 120 mg daily.

Dosage Adjustment

Dosage may be reduced for elderly patients and those with heart failure or impaired hepatic or renal function.

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Contraindications of Drug

Read contraindications if you want cheap Adalat (Nifedipine) online.

Hypersensitivity to a calcium channel blocker, second- or third-degree atrioventricular block without artificial pacemaker, sick sinus syndrome

Generic Drug Interactions

Drugs

anesthetics (hydrocarbon inhalation): Possibly hypotension

antiviral drugs, cimetidine, dalfopristin, diltiazem, erythromycin, fluconazole, itraconazole, ketoconazole, nefazodone, other antihypertensives, prazocin, quinupristin, timolol, valproic acid, verapamil: Increased risk of hypotension

benazepril: Possibly increased heart rate and hypotensive effect

beta blockers: Increased risk of profound hypotension, heart failure, and worsening of angina

calcium supplements: Possibly interference with action of nifedipine carbamazepine, nonsteroidal anti-inflammatory drugs (NSAIDs), phenobarbitone, phenytoin, rifampin, rifapentine, St. John's wort, sympathomimetics: Possibly decreased therapeutic effects of nifedipine digoxin: Transiently increased blood digoxin level, increased risk of digitalis toxicity disopyramide, flecainide: Increased risk of bradycardia, conduction defects, and heart failure

doxazocin: Decreased doxazocin effectiveness; increased nifedipine effectiveness estrogens: Possibly increased fluid retention and decreased nifedipine effects lithium: Increased risk of neurotoxicity metformin: Increased metformin absorption and plasma level

tacrolimus: Decreased tacrolimus metabolism

Foods

grapefruit, grapefruit juice: Possibly increased bio availability of nifedipine high-fat meals: Possibly delayed nifedipine absorption

Activities

alcohol use: Additive hypotensive effect

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Drugs Adverse Reactions

Central Nervous System: Anxiety, ataxia, confusion, dizziness, drowsiness, headache, nervousness (possibly extreme), nightmares, paresthesia, psychiatric disturbance, syncope, tremor, weakness

Cardiovascular: Arrhythmias (bradycardia, tachycardia), chest pain, heart failure, hypotension, palpitations, peripheral edema

Eyes, Ears, Nose, And Throat: Altered taste, blurred vision, dry mouth, epistaxis, gingival hyperplasia, nasal congestion, pharyngitis, sinusitis, tinnitus

Endocrine: Gynecomastia, hyperglycemia

Gastrointestinal: Anorexia, constipation, diarrhea, dyspepsia, elevated liver function test results, hepatitis, nausea, vomiting

Genitourinary: Dysuria, nocturia, polyuria, sexual dysfunction, urinary frequency

Hematologic: Anemia, leukopenia, positive Coombs' test, thrombocytopenia

Musculoskeletal: Joint stiffness, muscle cramps

Respiratory: Chest congestion, cough, dyspnea, respiratory tract infection, wheezing

Skin: Dermatitis, diaphoresis, erythema multiforme, flushing, photosensitivity, pruritus, rash, urticaria

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Nursing Considerations for Generic Drugs

• When starting and stopping nifedipine therapy, taper it, as prescribed, over 7 to 14 days.

• For closely monitored hospitalized patient with angina, dosage may be increased 10 mg every 4 to 6 hours to control chest pain.

• Because of drug's negative inotropic effect on some patients, frequently monitor heart rate and rhythm and blood pressure in patients who take a beta blocker or have heart failure or significant left ventricular dysfunction.

• Monitor fluid intake and output and daily weight; fluid retention may lead to heart failure. Also assess for signs of heart failure, such as crackles, dyspnea, jugular vein distention, peripheral edema, and weight gain.

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Nifedipine

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


British Pharmacopoeia, 2008 edition: Nifedipine Capsules;
The United States Pharmacopeia 31, 2008: Nifedipine Capsules; Nifedipine Extended-release Tablets.

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