Aleve (Naproxen)
Class and Category of Drug
Before you buy Aleve (Naproxen) online, read common information about the medication.
Chemical class: Propionic acid derivative
Therapeutic class: Analgesic, anti-inflammatory, antipyretic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Aleve (Naproxen) online , you must read how it works.
To relieve mild to moderate musculo-skeletal inflammation, including ankymusculoskeletal inflammation or pain
Delayed-Release Tablets, Oral Suspension, Tablets (Naproxen)
Adults. 250 to 500 mg b.i.d. Maximum: 1,500 mg daily for limited periods, as prescribed.
E.R. Tablets (Naproxen Sodium ) Adults. 750 to 1,000 mg daily. Maximum: 1,500 mg daily.
Tablets (Naproxen Sodium ) Adults. 275 to 550 mg b.i.d. Maximum: 1,650 mg daily for limited periods, as prescribed.
Suppositories (Naproxen Sodium ) Adults. 500 mg at bedtime in addition to daytime P.O. administration. Maximum: 1,500 mg daily (P.O. and suppository combined).
To relieve symptoms of juvenile rheumatoid arthritis and other inflammatory conditions in children
Oral Suspension, Tablets (Naproxen)
Children. 10 mg/kg daily in divided doses b.i.d.
To relieve symptoms of acute gouty arthritis
Delayed-Release Tablets, Oral Suspension, Tablets (Naproxen)
Adults. Initial: 750 mg, then 250 mg every 8 hr until symptoms subside. E.R.
Tablets (Naproxen Sodium ) Adults. Initial: 1,000 to 1,500 mg on day 1; then 1,000 mg daily until symptoms subside. Maximum: 1,500 mg daily.
Tablets (Naproxen Sodium ) Adults. Initial: 825 mg, then 275 mg every 8 hr until symptoms subside.
To relieve mild to moderate pain, including losing spondylitis, osteoarthritis, and rheumatoid arthritis acute tendinitis and bursitis, arthralgia, dysmenorrhea, and myalgia
Delayed-Release Tablets (Naproxen) Adults. Initial: 1,000 mg daily. Maximum: 1,500 mg daily.
E.R. Tablets (Naproxen Sodium ) Adults. Initial: 1,100 mg daily, increased as prescribed. Maximum: 1,500 mg daily. Oral Suspension, Tablets (Naproxen) Adults. Initial: 500 mg, then 250 mg every 6 to 8 hr, p.r.n. Maximum: 1,250 mg daily.
Tablets (Naproxen Sodium ) Adults. Initial: 550 mg, then 275 mg every 6 to 8 hr, p.r.n. Maximum: 1,375 mg daily.
To relieve fever and mild to moderate
Tablets (OTC Naproxen Sodium ) Adults. 220 mg every 8 to 12 hr; or 440 mg and 220 mg 12 hr later. Maximum: 660 mg daily for 10 days unless directed otherwise.
Dosage Adjustment For patients over age 65, 220 mg every 12 hr. Maximum: 440 mg for 10 days unless directed otherwise.
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Contraindications of Drug
Read contraindications if you want cheap Aleve (Naproxen) online.
Angioedema, asthma, bronchospasm, nasal polyps, rhinitis, or urticaria induced by aspirin, iodides, or other NSAIDs; hyper-sensitivity to naproxen or its components
Generic Drug Interactions
Drugs
ACE inhibitors: Decreased antihypertensive effects; increased risk of renal dysfunction acetaminophen: Increased risk of adverse renal effects with combined long-term use
aluminum hydroxide or magnesium oxide antacids, cholestyramine, sucralfate: Possibly delayed absorption of naproxen
anticoagulants, thrombolytics: Prolonged PT, increased risk of bleeding antihypertensives: Decreased effectiveness of antihypertensive
aspirin: Decreased aspirin effectiveness from lowered plasma and peak aspirin levels
For antirheumatism, onset is in 14 days, peak is unknown, and duration is 2 to 4 wk.
For analgesia.
For gout, 1 to 2 days.
beta blockers: Decreased antihypertensive effects of these drugs
bone marrow depressants, such as aldesleukin and cisplatin: Increased risk of leukopenia and thrombocytopenia
cefamandole, cefoperazone, cefotetan, plicamycin, valproic acid: Increased risk of hypoprothrombinemia and bleeding
cimetidine: Altered blood naproxen level
colchicine, glucocorticoids, other nonsteroidal anti-inflammatory drugs (NSAIDs), potassium supplements, salicylates: Increased gastrointestinal irritability and bleeding cyclosporine, gold compounds, nephrotoxic drugs: Increased risk of nephrotoxicity digoxin: Increased blood digoxin level and risk of digitalis toxicity
diuretics: Decreased diuretic effectiveness
furosemide: Decreased natriuretic effect
insulin, oral antidiabetic drugs: Increased effectiveness of these drugs; risk of hypoglycemia
lithium: Increased risk of lithium toxicity methotrexate: Increased risk of methotrex-ate toxicity
naproxen-containing products: Increased risk of toxicity
phenytoin: Increased blood phenytoin level probenecid: Increased risk of naproxen toxicity
Activities
alcohol use, smoking: Increased risk of naproxen-induced gastrointestinal ulceration
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Drugs Adverse Reactions
Central Nervous System: Aseptic meningitis, chills, cognitive impairment, decreased concentration, depression, dizziness, dream disturbances, drowsiness, fever, headache, insomnia, light-headedness, malaise, seizures, stroke, vertigo
Cardiovascular: Edema, heart failure, hypertension, MI, palpitations, tachycardia, vasculitis
Eyes, Ears, Nose, And Throat: Papilledema, papillitis, retrobulbar optic neuritis, stomatitis, tinnitus, vision or hearing changes
Endocrine: Hyperglycemia, hypoglycemia
Gastrointestinal: Abdominal pain, anorexia, colitis, constipation, diarrhea, diverticulitis, dyspepsia, dysphagia, elevated liver function test results, esophagitis, flatulence, gastritis, gastroenteritis, gastroesophageal reflux disease, gastrointestinal bleeding and ulceration, heartburn, hematemesis, hepatitis, indigestion, melena, nausea, pancreatitis, peptic ulceration, perforation of stomach or intestines, stomatitis, vomiting
Genitourinary: Elevated serum creatinine level, glomerulonephritis, hematuria, infertility (in women), interstitial nephritis, menstrual irregularities, nephrotic syndrome, renal failure, renal papillary necrosis
Hematologic: Agranulocytosis, anemia, aplastic anemia, eosinophilia, granulocytopenia, heinolytic anemia, leukopenia, neutropenia, pancytopenia, thrombocytopenia
Musculoskeletal: Muscle weakness, myalgia
Respiratory: Asthma, dyspnea, eosinophilic pneumonitis, respiratory depression
Skin: Alopecia, diaphoresis, ecchymosis, erythema multiforme, photosensitivity, pruritus, pseudoporphyria, purpura, rash, Stevens-Johnson syndrome, systemic lupus erythematosus, toxic epidermal necrolysis, urticaria
Other: Anaphylaxis, angioedema, hyper-kalemia
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Nursing Considerations for Generic Drugs
• Use naproxen with extreme caution in patients with a history of ulcer disease or gastrointestinal bleeding because NSAIDs such as naproxen increase risk of gastrointestinal bleeding and ulceration. Expect to use naproxen for the shortest time possible in these patients.
• Serious gastrointestinal tract ulceration, bleeding, and perforation may occur without warning symptoms. Elderly patients are at greater risk. To minimize risk, give drug with food. If gastrointestinal distress occurs, withhold drug and notify prescriber immediately.
• Use naproxen cautiously in patients with hypertension, and monitor blood pressure closely. Drug may cause hypertension or worsen it. Because of naproxen's sodium content, watch for fluid retention.
• Rehydrate a dehydrated patient before giving drug. If patient has renal disease, monitor renal function closely during therapy.
• Naproxen isn't recommended for patients with advanced renal of days
WARNING Monitor patient closely for thrombotic events, including MI and stroke, because NSAIDs increase the risk, especially if used in higher doses than recommended or for extended periods of time.
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