Amaryl (Glimepiride)
Class and Category of Drug
Before you buy Amaryl (Glimepiride) online, read common information about the medication.
Chemical class: Sulfonylurea
Therapeutic class: Antidiabetic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Amaryl (Glimepiride) online , you must read how it works.
To control blood glucose level in type 2 diabetes mellitus
Tablets Adults. 1 to 2 mg daily with first meal of the day. Maintenance: 1 to 4 mg daily, increased by 1 to 2 mg every 1 to 2 wk as needed for blood glucose control. Maximum: 8 mg daily.
Dosage Adjustment Initial dosage reduced to 1 mg daily if needed for patients with renal impairment.
As adjunct (with insulin) to control blood glucose level
Tablets Adults. 8 mg daily with low-dose insulin.
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Generic Drug Interactions
Drugs
ACE inhibitors, anabolic steroids, androgens, azole antifungals, bromocriptine, chloramphenicol, clarithromycin, disopyramide, fibric acid derivatives, fluoxetine, guanethidine, H2-receptor antagonists, insulin, magnesium salts, MAO inhibitors, methyldopa, nonsteroidal anti-inflammatory drugs (NSAIDs), octreotide, oral anticoagulants, oxyphenbuta-zone, phenylbutazone, probenecid, quinidine, quinolones, salicylates, sulfonamides, tetracycline, theophylline, tricyclic antidepressants, urinary acidifiers: Increased risk of hypoglycemia
asparaginase, calcium channel blockers, cholestyramine, clonidine, corticosteroids, danazol, diazoxide, estrogen, glucagon, hydantoins, isoniazid, lithium, morphine, nicotinic acid, oral contraceptives, phenothiazines, rifabutin, rifampin, sympathomimetics, thiazide diuretics, thyroid drugs, urinary alkalinizers: Increased risk of hyperglycemia
beta blockers: Possibly hyperglycemia or masking of hypoglycemia signs
digoxin: Increased risk of digitalis toxicity
pentamidine: Initially hypoglycemia and then hyperglycemia if beta cell damage occurs
Activities
alcohol use: Altered blood glucose control (usually hypoglycemia)
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, anxiety, asthenia, chills, depression, dizziness, fatigue, headache, hypertonia, hypoesthesia, insomnia, malaise, migraine headache, nervousness, paresthesia, somnolence, syncope, tremor, vertigo
Cardiovascular: Arrhythmias, edema, hypertension, vasculitis
Eyes, Ears, Nose, And Throat: Blurred vision, conjunctivitis, eye pain, pharyngitis, retinal hemorrhage, rhinitis, taste perversion, tinnitus
Endocrine: Hypoglycemia
Gastrointestinal: Anorexia, constipation, diarrhea, elevated liver function test results, epigastric discomfort or fullness, flatulence, heartburn, hunger, nausea, proctocolitis, trace blood in stool, vomiting
Genitourinary: Darkened urine, decreased libido, dysuria, polyuria
Hematologic: Agranulocytosis, aplastic anemia, eosinophilia, hemolytic anemia, hepatic porphyria, leukopenia, pancytopenia
Musculoskeletal: Arthralgia, leg cramps, myalgia
Respiratory: Dyspnea
Skin: Allergic skin reactions, diaphoresis, eczema, erythema multiforme, exfoliative dermatitis, flushing, jaundice, lichenoid reactions, maculopapular or morbiHiform rash, photosensitivity, pruritus, urticaria
Other: Disulfiram-like reaction
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Nursing Considerations for Generic Drugs
• Monitor fasting blood glucose level to determine response to glimepiride. Expect to check glycosylated hemoglobin level every 3 to 6 months to evaluate long-term blood glucose control.
• Arrange for dietary consultation and diabetic teaching, if appropriate. Ask dietitian to discuss amount of alcohol patient can consume without risking hypoglycemia.
• Expect to switch patient to insulin therapy, as prescribed, during physical stress, such as infection, surgery, and trauma.
WARNING Expect a higher risk of hypoglycemia when giving glimepiride to a malnourished or debilitated patient or one with renal, hepatic, pituitary, or adrenal insufficiency. Also be aware that hypo-glycemia may be more difficult to recognize in patients with autonomic neuropathy, the elderly, and patients taking beta blockers or other sympatholytic agents. Monitor blood glucose level closely.
• Monitor patient with a history of allergies to other sulfonamide derivatives closely because he may be allergic to glimepiride. If allergic reactions persist or worsen (dyspnea, drop in blood pressure, or shock), expect drug to be discontinued.
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Glimepiride
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
The United States Pharmacopeia 31, 2008: Glimepiride Tablets.
Proprietary Preparations
Argentina: Adiuvan; Amaryl; Endial; Glemaz; Gluceride; Glucopirida; Islopir; Lomet; Next Step;
Australia: Amaryl; Aylide; Diapride; Dimirel;
Austria: Amaryl;
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Belgium: Amarylle;
Brazil: Amaryl; Azulix; Bioglic; Diamellitis; Glimepibal; Glimepil; Glimeprid; Glimeran; Glimesec; Hipomeril;
Canada: Amaryl;
The pharmaceutical companies our pharmacies buy from follow strict WHO standards for GMP.
Chile: Amaryl; Glemaz; Glucomet;
Czech Republic: Amarwin; Amaryl; Amyx; Apo- Glimep; Eglymad; Glemid; GlimTek; Glymexan; Melyd; Metis; Oltar;
Denmark: Amaryl;
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Finland: Amaryl;
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France: Amarel;
Germany: Amaryl; Glimegamma; Glimerid;
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Greece: Dialosa; Glimepiron; Glimespes; Glimexin; Gliperin; Mepirid; Penoza; Pharlecon; Saccharofar; Solosa; Sucryl; Tipo II; Toremol;
Hong Kong: Amaryl; Diapride;
Hungary: Amaryl; Dialosa; Glempid; GlimeWin; Glindia; Gliprex; Limeral; Meglimid; Melyd; Sintecal;
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India: Amaryl; Betaglim; Diaglim; Euglim; Glimcip; Glimiprex; Glimitab; Glimulin; Glyree; Glyree M; Karmelitos;
Indonesia: Amadiab; Amaryl; Anpiride; Glamarol; Glimexal; Gluvas; Mapryl; Metrix; Relide;
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Italy: Amaryl; Solosa;
Malaysia: Amaryl; Diapride; Glimaryl; Glimin; Glimulin; Miaryl;
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Mexico: Amaryl; Glupropan; Zukedib;
Netherlands or Holland: Amaryl;
Norway: Amaryl;
New Zealand: Amaryl;
Philippines: Imerid; Norizec; Solosa;
Poland: Amaryl; Amyx; Avaron; Betaglid; Diaril; Glemid; Glibetic; Glibezid; Glidiamid; Glimehexal; Glimesan; Glipid; Limeral; Melyd; Oltar; Pemidal; Symglic;
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France: Amaryl; Glamaryl;
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India: Betaglim M; Exermet GM; Glimiprex MF; Glimulin-MF;
Indonesia: Avandaryl;
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