Amitriptyline
Class and Category of Drug
Before you buy Amitriptyline online, read common information about the medication.
Chemical class: Tertiary amine
Therapeutic class: Tricyclic antidepressant
Pregnancy category: D
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Drug Indications and Dosages
Before purchase Amitriptyline online , you must read how it works.
To relieve depression, especially when accompanied by anxiety and insomnia
Tablets
Adults and children over age 12. Outpatient: 75 mg daily in divided doses, increased to 150 mg daily, if needed. In-patient: 100 mg daily, gradually increased to 300 mg daily, if needed. Maintenance: 40 to 100 mg daily at bedtime.
Dosage Adjustment Maintenance dosage reduced to 10 mg t.i.d. plus 20 mg at bedtime for adolescent and elderly patients.
Contraindications of Drug
Read contraindications if you want cheap Amitriptyline online.
Acute recovery phase after MI, hypersensitivity to amitriptyline, MAO inhibitor therapy within 14 days
Generic Drug Interactions
Drugs
anticholinergics, epinephrine, norepinephepinerine: Increased effects of these drugs
barbiturates: Decreased amitriptyline level
carbamazepine: Decreased serum amitriptyline level and increased serum carbamazepine level, which increases therapeutic and toxic effects of carbamazepine
cimetidine, disulfiram, fluoxetine, fluvoxamine, haloperidol, H2-receptor antagonists, methylphenidate, oral contraceptives, paroxetine, phenothiazines, sertraline: Increased serum amitriptyline level
cisapride: Possibly prolonged QT interval and increased risk of arrhythmias
clonidine, guanethidine, and other antihypertensives: Decreased antihypertensive effects
dicumarol: Increased anticoagulant effect
levodopa: Decreased levodopa absorption; sympathetic hyperactivity, sinus tachycardia, hypertension, agitation
MAO inhibitors: Possibly seizures and death
thyroid replacement drugs: Arrhythmias and increased antidepressant effects
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Activities
alcohol use: Enhanced CNS depression smoking: Decreased amitriptyline effects
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Drugs Adverse Reactions
Central Nervous System: Anxiety, ataxia, coma, chills, delusions, disorientation, drowsiness, extrapyramidal reactions, fatigue, fever, headache,insomnia, nightmares, peripheral neuropathy, suicidal ideation, tremor
Cardiovascular: Arrhythmias (including prolonged atrioventricular conduction, heart block, and tachycardia), cardiomyopathy, hypertension, MI, nonspecific electrocardiogram changes, orthostatic hypotension, palpitations
Eyes, Ears, Nose, And Throat: Abnormal taste, black tongue, blurred vision, dry mouth, increased salivation, nasal congestion, tinnitus
Endocrine: Gynecomastia, increased or decreased blood glucose level, increased prolactin level, syndrome of inappropriate ADH secretion
Gastrointestinal: Abdominal cramps, constipation, diarrhea, flatulence, ileus, increased appetite, nausea, vomiting
Genitourinary: Impotence, libido changes, menstrual irregularities, testicular swelling, urinary hesitancy, urine retention
Hematologic: Agranulocytosis, bone marrow depression, eosinophilia, leukopenia, thrombocytopenia
Skin: Alopecia, flushing, purpura
Other: Weight gain
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Nursing Considerations for Generic Drugs
• Because of amitriptyline's atropine-like effects, use caution if patient has a history of seizures, urine retention, or angle-closure glaucoma.
WARNING Don't give an MAO inhibitor within 14 days of amitriptyline because of the risk of seizures and death.
• Closely monitor patient with CV disorder because amitriptyline may cause arrhythmias, such as sinus tachycardia.
• Watch patients closely (especially children, adolescents, and young adults), for suicidal tendencies, particularly when therapy starts and dosage changes. Depression may worsen temporarily during these times.
• Monitor blood pressure for hypotension or hypertension.
• Stay alert for behavior changes, such as hallucinations and decreased interest in personal appearance. Be aware that psychosis may develop in schizophrenic patients, and symptoms may increase in paranoid patients.
• Abrupt withdrawal after long use may cause nausea, headache, vertigo, and nightmares.
Do I need a prescription to buy generic Amitriptyline in your online drug store?
No. You can buy Amitriptyline without a prescription!
