Anafranil (Clomipramine)
Class and Category of Drug
Before you buy Anafranil (Clomipramine) online, read common information about the medication.
Chemical class: Dibenzazepine derivative
Therapeutic class: Antiobsessional tricyclic antidepressant
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Anafranil (Clomipramine) online , you must read how it works.
To treat obsessive-compulsive disorder
Capsules,Tablets
Adults. Initial: 25 mg daily. Gradually increased to 100 mg daily in divided doses over 2 wk, then to maximum of 250 mg daily in divided doses over next few weeks.
At maximum dose, total daily amount may be given at bedtime.
Children age 10 and over. Initial: 25 mg daily. Gradually increased to the lesser of 3 mg/kg daily or 100 mg daily in divided doses over 2 wk, then to maximum of 3 mg/kg daily or 200 mg daily, whichever is less. At maximum dose, total daily amount may be given at bedtime.
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Contraindications of Drug
Read contraindications if you want cheap Anafranil (Clomipramine) online.
Acute recovery period after MI, hypersensitivity to clomipramine or its components, use of an MAO inhibitor within 14 days
Generic Drug Interactions
Drugs
anticholinergics: Increased anticholinergic effects
barbiturates: Decreased level and effects of clomipramine; additive CNS depression
bupropion, cimetidine, haloperidol, H2-receptor antagonists, selective serotonin reuptake inhibitors, valproic acid: Increased blood level and therapeutic and adverse effects of clomipramine
carbamazepine: Decreased blood clomipramine level; increased carbamazepine level
clonidine: Severely increased blood pressure and risk of hypertensive crisis
CNS depressants: Increased CNS depression dicumarol: Increased anticoagulant effect
grepafloxacin, quinolones, sparfloxacin: Increased risk of life-threatening arrhythmias
guanethidine: Antagonized antihypertensive effect of guanethidine
levodopa: Delayed absorption and decreased bioavailability of levodopa
MAO inhibitors: Increased risk of seizures, coma, or death
rifamycins: Decreased clomipramine level sympathomimetics: Possibly potentiated cardiovascular effects
thyroid drugs: Increased effects of thyroid drugs and clomipramine
Activities
alcohol use: Increased CNS depression
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Drugs Adverse Reactions
Central Nervous System: Anxiety, confusion, depersonalization, depression, dizziness, drowsiness, emotional lability, fatigue, headache, insomnia, panic reaction, paresthesia, somnolence, suicidal ideation (children and teens), syncope, tremor, unusual dreams, yawning
Cardiovascular: Orthostatic hypotension, palpitations, tachycardia
Eyes, Ears, Nose, And Throat: Blurred vision, dry mouth, epistaxis, pharyngitis, rhinitis, sinusitis, unpleasant taste
Gastrointestinal: Abdominal pain, anorexia, constipation, diarrhea, flatulence, increased appetite, indigestion, nausea, vomiting
Genitourinary: Dysmenorrhea, ejaculation failure, impotence, urinary hesitancy, urine retention
Respiratory: Bronchospasm
Skin: Abnormal skin odor, acne, dermatitis, dry skin, photosensitivity, rash, urticaria
Other: Weight gain
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Nursing Considerations for Generic Drugs
• Be aware that stopping clomipramine abruptly may cause withdrawal symptoms and worsen disorder.
WARNING Don't give drug within 14 days of an MAO inhibitor to avoid possible seizures, coma, or death. WARNING Monitor children and teens closely for evidence of suicidal ideation; clomipramine increases the risk in these groups.
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Clomipramine
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
British Pharmacopoeia, 2008 edition: Clomipramine Capsules;
The United States Pharmacopeia 31, 2008: Clomipramine Hydrochloride Capsules.
Proprietary Preparations
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