Aricept (Donepezil)
Class and Category of Drug
Before you buy Aricept (Donepezil) online, read common information about the medication.
Chemical class: Piperidine derivative
Therapeutic class: Antidementia
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Aricept (Donepezil) online , you must read how it works.
To treat dementia of Alzheimer's type
Oral Solution,Tablets
Adults. Initial: 5 mg at bedtime. After 4 to 6 wk, dosage increased to 10 mg at bedtime, as indicated. Maximum: 10 mg daily.
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Contraindications of Drug
Read contraindications if you want cheap Aricept (Donepezil) online.
Hypersensitivity to donepezil, piperidine derivatives, or their components
Generic Drug Interactions
Drugs
anticholinergics: Possibly interference with activity of these drugs
carbamazepine, dexamethasone, phenobarbital, phenytoin, rifampin: Increased donepezil elimination rate
cholinergic agonists, neuromuscular blockers:Possibly synergistic effects of these drugs
ketoconazole, quinidine: Inhibited donepezil metabolism
NSAIDs: Possibly increased gastric acid secretion and increased risk of gastrointestinal bleeding
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, agitation, anxiey, asthenia, depression, dizziness, dream disturbances, fatigue, fever, headache, hostility, insomnia, nervousness, seizures, somnolence, syncope, tremor
Cardiovascular: Abnormal electrocardiogram, bradycardia, chest pain, edema, heart failure, hypertension, hypotension
Eyes, Ears, Nose, And Throat: Pharyngitis
Endocrine: Hyperglycemia
Gastrointestinal: Abdominal pain, anorexia, constipation, diarrhea, dyspepsia, gastroenteritis, fecal incontinence, nausea, vomiting
Genitourinary: Cystitis, glycosuria, hematuria, urinary frequency or incontinence, urinary tract infection
Hematologic: Anemia, hemorrhage
Musculoskeletal: Arthralgia, back pain, elevated creatine kinase level, muscle spasms
Respiratory: Bronchitis, increased cough, pneumonia
Skin: Ecchymosis, eczema, pruritus, rash, ulceration
Other: Angioedema, dehydration, elevated alkaline phosphatase or lactate dehydroge-nase level, flu syndrome, weight loss
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Nursing Considerations for Generic Drugs
• Use donepezil cautiously in patients with bladder obstruction because drug's weak peripheral cholinergic effect could obstruct outflow.
• Use drug cautiously in patients with asthma, COPD, or other pulmonary disorders because it has weak affinity for peripheral cholinesterase, which may increase bronchoconstriction and bronchial secretions.
• If patient has cardiac disease, monitor heart rate and rhythm for bradycardia, which may result from increased vagal tone caused by drug's inhibition of peripheral cholinesterase. Reduced heart rate may be especially significant if patient has sick sinus syndrome, bradycardia, or other supraventricular arrhythmia.
• Take safety precautions if patient is dizzy or has other adverse CNS reactions.
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Donepezil
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
Proprietary Preparations
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