Artane (Trihexyphenidyl)
Class and Category of Drug
Before you buy Artane (Trihexyphenidyl) online, read common information about the medication.
Chemical class: Tertiary amine
Therapeutic class: Antidyskinetic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Artane (Trihexyphenidyl) online , you must read how it works.
To treatparkinsonism
Elixir, Tablets
Adults. Initial: 1 to 2 mg on day 1, divided into 3 equal doses and given with meals. Total daily dose increased by 2 mg every 3 to 5 days until desired response or maximum dose is reached. Maximum: 15 mg daily.
E.R. Capsules
Adults. 5 mg after breakfast; additional 5 mg 12 hr later, if needed. Maximum: 15 mg daily.
To treat drug-induced extrapyramidal symptoms
Tablets
Adults. 1 mg daily, increased to 5 to 15 mg/ day, as prescribed, to control symptoms.
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Contraindications of Drug
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Achalasia, bladder neck or prostatic obstruction, narrow-angle glaucoma, hyper-sensitivity to trihexyphenidyl or its components, megacolon, myasthenia gravis, pyloric or duodenal obstruction, stenosing peptic ulcer
Generic Drug Interactions
Drugs
amantadine, anticholinergics, MAO inhibitors, tricyclic antidepressants: Increased anti-cholinergic effects
antidiarrheals (adsorbent): Possibly decreased therapeutic effects of trihexyphenidyl
chlorpromazine: Decreased blood chlorpromazine level
CNS depressants: Increased sedative effect
levodopa: Increased efficacy of levodopa
Activities
alcohol use: Increased sedation
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Drugs Adverse Reactions
Central Nervous System: Confusion, dizziness, drowsiness,nervousness
Eyes, Ears, Nose, And Throat: Blurred vision; dry eyes, mouth, nose, or throat; mydriasis
Gastrointestinal: Constipation, nausea, vomiting
Genitourinary: Dysuria, urine retention
Skin: Decreased sweating
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Nursing Considerations for Generic Drugs
• Use trihexyphenidyl cautiously in patients with cardiovascular, hepatic, or renal disorders. Patients with cardiovascular disorders, such as atherosclerosis, hypertension, and ischemic heart disease, are at risk for tachycardia and coronary ischemia from drug's positive chronotropic effects. Hepatic and renal dysfunction increase the risk of adverse reactions.
• Before therapy begins, assess patient's muscle rigidity and tremor to establish a baseline. During therapy, reassess patient to detect improvement in these signs and evaluate drug effectiveness.
• Obtain patient's intraocular pressure before and periodically during trihexyphenidyl therapy, as ordered, because drug can precipitate incipient glaucoma.
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Trihexyphenidyl
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
British Pharmacopoeia, 2008 edition: Trihexyphenidyl Tablets;
The United States Pharmacopeia 31, 2008: Trihexyphenidyl Hydrochloride Elixir; Trihexyphenidyl Hydrochloride Extended-release Capsules; Trihexyphenidyl Hydrochloride Tablets.
Proprietary Preparations
Argentina: Artane;
Australia: Artane;
Austria: Artane;
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