Avandamet (Rosiglitazone maleate)
Class and Category of Drug
Before you buy Avandamet (Rosiglitazone maleate) online, read common information about the medication.
Chemical class: Thiazolidinedione
Therapeutic class: Antidiabetic drug
Pregnancy category: C
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Drug Indications and Dosages
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To achieve glucose control in type 2 diabetes mellitus as monotherapy or in combination with insulin therapy
Tablets
Adults. 4 mg daily with no change in insulin dosage. Insulin dosage decreased by 10% to 25% if hypoglycemia occurs or fasting plasma concentrations decrease to less than 100 mg/dl with combination therapy.
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Contraindications of Drug
Read contraindications if you want cheap Avandamet (Rosiglitazone maleate) online.
Hypersensitivity to rosiglitazone or its components, New York Heart Association (NYHA) class III or IV heart failure
Generic Drug Interactions
Drugs
CYP2C8 inducers, such as rifampin: Possibly decreased effects of rosiglitazone CYP2C8 inhibitors, such as gemfibrozil: Possibly increased effects of rosiglitazone
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Drugs Adverse Reactions
Central Nervous System: Fatigue, headache
Cardiovascular: Angina, congestive heart failure, edema, hypertension, myocardial ischemia or infarction
Eyes, Ears, Nose, And Throat: Blurred vision, decreased visual acuity, macular edema, nasopharyngitis, sinusitis
Endocrine: Hyperglycemia, hypoglycemia
Gastrointestinal: Diarrhea, elevated liver enzymes, hepatotoxicity
Hematologic: Anemia
Musculoskeletal: Arthralgia, back pain, fracture (women)
Respiratory: Dyspnea, upper respiratory tract infection
Skin: Pruritus, rash, Stevens-Johnson syndrome, urticaria
Other: Anaphylaxis, angioedema, weight gain
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Nursing Considerations for Generic Drugs
Give rosiglitazone cautiously in patients with edema, heart failure, or hepatic impairment because of potential adverse reactions.
Be aware that drug isn't recommended for with symptomatic heart failure.
Evaluate patient's liver function before starting drug and periodically throughout therapy, as ordered. Notify prescriber about abnormalities, such as nausea, vomiting, abdominal pain, fatigue, anorexia, and dark urine. Drug may need to be stopped.
WARNING Monitor patient for evidence of congestive heart failure such as shortness of breath, rapid weight gain, or edema because rosiglitazone can cause fluid retention that may lead to or worsen heart failure. Notify prescriber immediately if the patient's cardiac status deteriorates, and expect to stop the drug, as ordered.
Monitor fasting glucose and glycosylated hemoglobin Alc levels periodically, as ordered, to evaluate rosiglitazone effectiveness.
Be aware that drug is effective only in the presence of endogenous insulin.
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