Avandia (Rosiglitazone maleate) - Anti-Diabetic
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Top » Catalog » Anti-Diabetic » Avandia (Rosiglitazone maleate)


Avandia (Rosiglitazone maleate)

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Avandia (Rosiglitazone maleate)

Class and Category of Drug

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Chemical class: Thiazolidinedione

Therapeutic class: Antidiabetic drug

Pregnancy category: C

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Drug Indications and Dosages

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To achieve glucose control in type 2 diabetes mellitus as monotherapy or in combination with insulin therapy

Tablets

Adults. 4 mg daily with no change in insulin dosage. Insulin dosage decreased by 10% to 25% if hypoglycemia occurs or fasting plasma concentrations decrease to less than 100 mg/dl with combination therapy.

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Contraindications of Drug

Read contraindications if you want cheap Avandia (Rosiglitazone maleate) online.

Hypersensitivity to rosiglitazone or its components, New York Heart Association (NYHA) class III or IV heart failure

Generic Drug Interactions

Drugs

CYP2C8 inducers, such as rifampin: Possibly decreased effects of rosiglitazone CYP2C8 inhibitors, such as gemfibrozil: Possibly increased effects of rosiglitazone

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Drugs Adverse Reactions

Central Nervous System: Fatigue, headache

Cardiovascular: Angina, congestive heart failure, edema, hypertension, myocardial ischemia or infarction

Eyes, Ears, Nose, And Throat: Blurred vision, decreased visual acuity, macular edema, nasopharyngitis, sinusitis

Endocrine: Hyperglycemia, hypoglycemia

Gastrointestinal: Diarrhea, elevated liver enzymes, hepatotoxicity

Hematologic: Anemia

Musculoskeletal: Arthralgia, back pain, fracture (women)

Respiratory: Dyspnea, upper respiratory tract infection

Skin: Pruritus, rash, Stevens-Johnson syndrome, urticaria

Other: Anaphylaxis, angioedema, weight gain

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Nursing Considerations for Generic Drugs

• Give rosiglitazone cautiously in patients with edema, heart failure, or hepatic impairment because of potential adverse reactions.

• Be aware that drug isn't recommended for with symptomatic heart failure.

• Evaluate patient's liver function before starting drug and periodically throughout therapy, as ordered. Notify prescriber about abnormalities, such as nausea, vomiting, abdominal pain, fatigue, anorexia, and dark urine. Drug may need to be stopped.

WARNING Monitor patient for evidence of congestive heart failure — such as shortness of breath, rapid weight gain, or edema — because rosiglitazone can cause fluid retention that may lead to or worsen heart failure. Notify prescriber immediately if the patient's cardiac status deteriorates, and expect to stop the drug, as ordered.

• Monitor fasting glucose and glycosylated hemoglobin Alc levels periodically, as ordered, to evaluate rosiglitazone effectiveness.

• Be aware that drug is effective only in the presence of endogenous insulin.

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Rosiglitazone

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


Proprietary Preparations


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