Avapro (Irbesartan)
Class and Category of Drug
Before you buy Avapro (Irbesartan) online, read common information about the medication.
Chemical class: Nonpeptide angiotensin II antagonist
Therapeutic class: Antihypertensive
Pregnancy category: D
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Drug Indications and Dosages
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To manage hypertension, alone or with other antihypertensives
Tablets
Adults and adolescents. Initial: 150 mg daily.
Maximum: 300 mg daily.
Dosage Adjustment Initial dosage reduced to 75 mg daily for patients with hypovolemia or hyponatremia from such causes as hemodialysis or vigorous diuretic therapy.
Children ages 6 to 12. Initial: 75 mg daily. Maximum: 150 mg daily.
To treat nephropathy in type 2 diabetes mellitus
Tablets Adults. 300 mg daily.
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Contraindications of Drug
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Hypersensitivity to irbesartan or its components
Generic Drug Interactions
Drugs
diuretics: Possibly additive hypotensive effects
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Drugs Adverse Reactions
Central Nervous System: Anxiety, dizziness, fatigue, headache, nervousness
Cardiovascular: Chest pain, hypotension, peripheral edema, tachycardia
Eyes, Ears, Nose, And Throat: Pharyngitis, rhinitis
Gastrointestinal: Abdominal pain, diarrhea, heartburn, hepatitis, indigestion, nausea, vomiting
Genitourinary: Urinary tract infection
Musculoskeletal: Musculoskeletal pain
Respiratory: Upper respiratory tract infection
Skin: Rash
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Nursing Considerations for Generic Drugs
• If patient has known or suspected hypovolemia, provide treatment, such as intravenous normal saline solution, as prescribed, to correct this condition before beginning irbesartan therapy. Or expect to begin therapy with a lower dosage.
• Check blood pressure often to evaluate drug's effectiveness.
• If blood pressure isn't controlled with irbesartan alone, expect to also give a diuretic, such as hydrochlorothiazide, as prescribed.
WARNING If patient receives a diuretic or another antihypertensive during irbesartan therapy, frequently monitor blood pressure because he's at risk for hypotension.
• If patient experiences symptomatic hypotension, expect to stop drug temporarily. Immediately place him in supine position and prepare to give intravenous normal saline solution, as prescribed. Expect to resume drug therapy after blood pressure stabilizes.
• If patient receives a diuretic, provide adequate hydration, as appropriate, to help prevent hypovolemia. Also monitor patient for signs and symptoms of hypovolemia, such as hypotension, dizziness, and fainting.
WARNING Monitor patient for increased BUN and serum creatinine levels if he has heart failure or impaired renal function because drug may cause acute renal failure. If increases are significant or persistent, notify prescriber immediately.
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Irbesartan
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
The United States Pharmacopeia 31, 2008: Irbesartan and Hydrochlorothiazide Tablets; Irbesartan Tablets.
Proprietary Preparations
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Multi-ingredient
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