Calcium Carbonate (Apo-Cal)
Class and Category of Drug
Before you buy Calcium Carbonate (Apo-Cal) online, read common information about the medication.
Chemical class: Elemental cation
Therapeutic class: Antacid, antihypermagnesemic, antihyperphosphatemic, antihypocalcemic, calcium replacement, cardiotonic
Pregnancy category: C (Not rated for calcium carbonate, citrate, and lactate)
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Drug Indications and Dosages
Before purchase Calcium Carbonate (Apo-Cal) online , you must read how it works.
To treat hyperphosphatemia
Tablets (Calcium Acetate)
Adults.
Initial: 2 tablets (338 mg elemental calcium, 1,334 mg calcium acetate) t.i.d. with meals. Dosage increased to reduce serum phosphorus level below 6 mg/dl as long as hypercalcemia doesn't develop. Maintenance: 3 or 4 tablets t.i.d. with each meal.
To prevent hypocalcemia
Capsules, Oral Suspension, Tablets (Calcium Carbonate); Effervescent Tablets, Tablets (Calcium Citrate); Syrup (Calcium Glubionate); Tablets (Calcium Gluconate or Lactate)
Adults and children over age 10. 800 to 1,200 mg daily.
Pregnant and breast-feeding women. 1,200 mg daily.
Children ages 4 to 10. 800 mg daily. Children up to age 4. 400 to 800 mg daily.
To provide antacid effects
Chewable Tablets, Oral Suspension, Tablets (Calcium Carbonate)
Adults and children age 12 and over. 350 to 1,500 mg 1 hr after meals and at bedtime, p.r.n.
To replace calcium in hypocalcemia
I.V. Infusion (Calcium Chloride)
Adults. 0.5 to 1 g every 1 to 3 days, infused at less than 1 ml/min.
Children. 25 mg/kg given over several minutes.
Intravenous or Intramuscular Injection (Calcium Gluceptate)
Adults and children. 0.44 to 1.1 g intramuscular or 1.1 to 4.4 g intravenous at a rate of no more than 2 ml (36 mg)/min.
Intravenous Injection (Calcium Gluconate)
Adults. 970 mg given slowly, repeated if needed, until tetany is controlled.
Children. 200 to 500 mg as a single dose given slowly, repeated if needed, until tetany is controlled.
As adjunct to treat magnesium intoxication
Intravenous Injection (Calcium Chloride)
Adults. 500 mg promptly and repeated p.r.n., based on response.
As adjunct in cardiac resuscitation
Intravenous Injection (Calcium Chloride)
Adults. 0.5 to 1 g.
Children. 0.2 ml/kg.
As adjunct in exchange transfusion
Intravenous Injection (Calcium Gluconate)
Adults. 1.35 mEq with each 100 ml of titrated blood exchanged.
Neonates. 0.45 mEq after each 100 ml of titrated blood exchanged.
Intravenous Injection (Calcium Gluceptate)
Neonates. 110 mg after each 100 ml of titrated blood exchanged.
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Contraindications of Drug
Read contraindications if you want cheap Calcium Carbonate (Apo-Cal) online.
Hypercalcemia, hypersensitivity to calcium salts or their components, hypophosphatemia, renal calculi
Incompatibilities
To avoid precipitation, don't give intravenous calcium chloride, gluceptate, or gluconate through same intravenous line as bicarbonates, carbonates, phosphates, sulfates, or tartrates.
Generic Drug Interactions
Drugs
aluminum-containing antacids: Enhanced aluminum absorption with use of calcium citrate
atenolol: Decreased blood atenolol level and beta blockade
calcitonin: Possibly antagonized effects of calcitonin in hypercalcemia treatment calcium supplements, magnesium-containing preparations: Increased serum calcium or magnesium level, especially in patients with impaired renal function
cellulose sodium phosphate: Decreased effectiveness of cellulose sodium phosphate in preventing hypercalciuria
digitalis glycosides: Increased risk of arrhythmias
estrogens, oral contraceptives (estrogen-containing): Increased calcium absorption
etidronate: Decreased etidronate absorption
fluoroquinolones: Reduced fluoroquinolone absorption by calcium carbonate gallium nitrate: Antagonized effects of gallium nitrate
iron salts: Decreased gastric iron absorption
magnesium sulfate (parenteral): Neutralized effects of magnesium by parenteral calcium neuromuscular blockers (except succinylcholine): Possibly reversal of neuromuscular blockade by parenteral calcium salts; enhanced or prolonged neuromuscular blockade induced by tubocurarine
norfloxacin: Decreased norfloxacin bioavailability
phenytoin: Decreased bioavailability of phenytoin and calcium potassium phosphates, potassium and sodium phosphates: Increased risk of calcium deposition in soft tissue
sodium bicarbonate: Possibly milk-alkali syndrome
sodium fluoride: Reduced fluoride and calcium absorption
sodium polystyrene sulfonate: Possibly metabolic alkalosis if patient has renal impairment tetracyclines: Decreased tetracycline absorption and blood level, leading to decreased anti-infective response
thiazide diuretics: Possibly hypercalcemia
verapamil: Reversed verapamil effects
vitamin A (more than 25,000 units daily): Possibly stimulation of bone loss, decreased effects of calcium supplementation, and hypercalcemia
vitamin D (high doses): Excessively increased calcium absorption
Foods
caffeine, high-fiber food: Possibly decreased calcium absorption
Activities
alcohol use (excessive), smoking: Possibly decreased calcium absorption
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Drugs Adverse Reactions
Central Nervous System: Paresthesia (parenteral form)
Cardiovascular: Hypotension, irregular heartbeat (parenteral form)
Gastrointestinal: Nausea or vomiting (parenteral form)
Skin: Diaphoresis, flushing, or sensation of warmth (parenteral form)
Other: Hypercalcemia; injection site burning, pain, rash, or redness (parenteral form)
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Nursing Considerations for Generic Drugs
• Store at room temperature, and protect from heat, moisture, and direct light. Don't freeze.
• Warm solution to room temperature before parenteral administration.
• Keep patient in a recumbent position for 30 minutes after parenteral administration to prevent dizziness from hypotension.
• Administer intravenous calcium through an infusing intravenous solution using a small-bore needle inserted into a large vein to minimize irritation. Give calcium slowly to prevent excess calcium from reaching the heart and causing adverse cardiovascular reactions. Adverse reactions often result from too-rapid administration. If electrocardiogram tracings are abnormal or patient reports injection site discomfort, expect to temporarily discontinue administration.
• Check regularly for infiltration because calcium causes necrosis. If infiltration occurs, stop infusion and tell prescriber immediately.
• Divide intramuscular calcium gluceptate dose of 5 ml or more in half and inject in gluteal region.
• Regularly monitor serum calcium level and evaluate therapeutic response by assessing for Chvostek's and Trousseau's signs, which shouldn't appear.
• Be aware that calcium chloride injection contains three times as much calcium per milliliter as calcium gluconate injection.
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