Capoten (Captopril) - Blood Pressure/Cholesterol
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Capoten (Captopril)

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Capoten (Captopril)

Class and Category of Drug

Before you buy Capoten (Captopril) online, read common information about the medication.

Chemical class: ACE inhibitor

Therapeutic class: Antihypertensive

Pregnancy category: C (first trimester), D (later trimesters)

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Drug Indications and Dosages

Before purchase Capoten (Captopril) online , you must read how it works.

To control hypertension

Tablets

Adults and adolescents. Initial: 25 mg b.i.d. or t.i.d. Increased to 50 mg b.i.d. or t.i.d. after 1 to 2 wk, if needed. If blood pressure isn't well controlled at this dosage and with the addition of a diuretic, dosage increased to 100 mg b.i.d. or t.i.d. and then, if needed, to 150 mg b.i.d. or t.i.d. while continuing diuretic. Maximum: 450 mg daily.

To control accelerated or malignant hypertension when temporary discontinuation of current antihypertensive therapy isn't practical or when prompt titra-tion of blood pressure is needed

Adults and adolescents. Initial: 25 mg b.i.d. or t.i.d while continuing diuretic but discontinuing current antihypertensive drug. Increased every 24 hr as needed until satisfactory response is obtained or maximum dosage is reached. Maximum: 450 mg daily.

To treat heart failure that's unresponsive to conventional therapy

Tablets

Adults and adolescents. Initial: 25 mg b.i.d. or t.i.d. Increased to 50 mg b.i.d. or t.i.d., as needed. After 14 days, increased to 100 mg t.i.d. and then to 150 mg t.i.d, if needed. Maximum: 450 mg daily.

To treat left-sided heart failure after MI

Tablets

Adults and adolescents. Initial: 6.25 mg as single dose starting 3 days after MI and then 12.5 mg t.i.d. Increased to 25 mg t.i.d. for several days and then again to maintenance dosage. Maintenance: 50 mg t.i.d.

To treat diabetic nephropathy

Tablets

Adults and adolescents. 25 mg t.i.d.

Dosage Adjustment Starting dosage reduced to 6.25 mg b.i.d. or t.i.d. if patient with hypertension also has heart failure, is undergoing dialysis, or is being vigorously treated with diuretics that result in hyponatremia or hypovolemia.

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Contraindications of Drug

Read contraindications if you want cheap Capoten (Captopril) online.

Hypersensitivity to captopril, other ACE inhibitors, or their components

Generic Drug Interactions

Drugs

allopurinol: Increased risk of hypersensitivity reactions, including Stevens-Johnson syndrome, skin eruptions, fever, arthralgia

antacids: Possibly impaired captopril absorption

capsaicin: Possibly cause or worsening of cough from ACE inhibitor

cyclosporine, potassium-containing drugs, potassium-sparing diuretics, potassium supplements: Increased risk of hyperkalemia

digoxin: Increased blood digoxin level

diuretics; hypotension-producing drugs, such as hydralazine: Additive hypotensive effects

gold: Increased risk of nitritoid reaction, including facial flushing, nausea, vomiting, and hypotension

lithium: Increased risk of lithium toxicity NSAIDs: Decreased antihypertensive response to ACE inhibition

probenecid: Increased blood level and decreased total clearance of captopril

Activities

alcohol use: Additive hypotensive effects

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Drugs Adverse Reactions

Central Nervous System: Fever

Cardiovascular: Chest pain, hypotension, orthostatic hypotension, palpitations, tachycardia

Eyes, Ears, Nose, And Throat: Loss of taste

Genitourinary: Dysuria, impotence, nephrotic syndrome, nocturia, oliguria, polyuria, proteinuria, urinary frequency

Hematologic: Eosinophilia

Musculoskeletal: Arthralgia

Respiratory: Cough

Skin: Photosensitivity, pruritus, rash

Other: Angioedema, hyperkalemia, hyponatremia, positive ANA titer

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Nursing Considerations for Generic Drugs

• Closely monitor patient's blood pressure, especially when therapy starts and dosage increases. Keep patient supine if hypotension occurs.

• Monitor renal function tests for signs of nephrotic syndrome, such as proteinuria and increased BUN and serum creatinine levels. Also watch for such renal evidence as oliguria, polyuria, and urinary frequency.

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Captopril

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


British Pharmacopoeia, 2008 edition: Captopril Tablets;
The United States Pharmacopeia 31, 2008: Captopril and Hydrochlorothiazide Tablets; Captopril Oral Solution; Captopril Oral Suspension; Captopril Tablets.

Proprietary Preparations


Argentina: Antasten;
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Multi-ingredient


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