Cardizem (Diltiazem)
Class and Category of Drug
Before you buy Cardizem (Diltiazem) online, read common information about the medication.
Chemical class: Benzothiazepine derivative
Therapeutic class: Antianginal, antiarrhythmic, antihypertensive
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Cardizem (Diltiazem) online , you must read how it works.
To treat Prinzmetal's (variant) angina and chronic stable angina
Tablets
Adults and adolescents. Initial: 30 mg t.i.d. or q.i.d. before meals and at bedtime, increased every 1 or 2 days as appropriate. Maximum: 360 mg daily in divided doses t.i.d. or q.i.d.
Extended-Release Tablets
Adults and adolescents. Initial: 180 mg daily, increased every 7 to 14 days as needed. Maximum: 360 mg daily.
To control hypertension
E.R. Capsules
Adults and adolescents. Initial: 180 to 240 mg daily, adjusted after 14 days as appropriate. Maximum: 360 mg daily.
Sustained-Release Capsules
Adults and adolescents. Initial: 60 to 120 mg b.i.d., adjusted after 14 days as appropriate. Maximum: 360 mg daily.
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Tablets
Adults and adolescents. Initial: 30 mg t.i.d. or q.i.d. before meals and at bedtime, increased every 1 or 2 days as appropriate. Maximum: 360 mg daily in divided doses t.i.d. or q.i.d.
Extended-Release Tablets
Adults. Initial: 180 to 240 mg daily, adjusted after 14 days, as needed. Maximum: 540 mg daily.
To treat atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia
Intravenous Infusion or Injection
Adults and adolescents. 0.25 mg/kg given by bolus over 2 min. If response is inadequate after 15 min, 0.35 mg/kg given by bolus over 2 min. Then 10 mg/hr for continued reduction of heart rate after bolus, increased by 5 mg/hr, as needed. Maximum: 15 mg/hr for up to 24 hr.
Incompatibilities
Don't give diltiazem through same intravenous line as acetazolamide, acyclovir, aminophylline, ampicillin sodium/sulbactam sodium, cefamandole, cefoperazone, diazepam, furosemide, heparin, hydrocortisone sodium succinate, methylprednisolone sodium succinate, mezlocillin, nafcillin, phenytoin, rifampin, or sodium bicarbonate.
Contraindications of Drug
Read contraindications if you want cheap Cardizem (Diltiazem) online.
Acute MI; cardiogenic shock; Lown-Ganong-Levine or Wolff-Parkinson-White syndrome, second- or third-degree atrioventricular block, and sick sinus syndrome, unless artificial pacemaker is in place; pulmonary edema; systolic blood pressure below 90 mm Hg; ventricular tachycardia (wide complex)
Generic Drug Interactions
Drugs
anesthetic: Additive hypotension; possibly decreased cardiac contractility, conductivity, and automaticity
benzodiazepines: Increased risk of prolonged sedation
beta blockers: Possibly increased risk of adverse cardiovascular effects
buspirone: Increased effects and risk of buspirone toxicity
carbamazepine, cyclosporine, lovastatin, quinidine, theophyllines: Decreased hepatic clearance and increased serum levels of these drugs, leading to toxicity
cimetidine: Decreased diltiazem metabolism, increased blood diltiazem level digoxin: Increased blood digoxin level
lithium: Possibly neurotoxicity
NSAIDs: Possibly antagonized antihypertensive effect of diltiazem
prazocin: Possibly increased risk of hypotension
procainamide: Possibly increased risk of prolonged QT interval
quinidine: Increased risk of adverse quinidine effects
rifampin: Decreased blood diltiazem level to undetectable amounts
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, amnesia, asthenia, depression, dizziness, dream disturbances, extrapyramidal reactions, fatigue, hallucinations, headache, insomnia, nervousness, paresthesia, personality change, somnolence, syncope, tremor, weakness
Cardiovascular: Angina, atrial flutter, atrioventricular block (first-, second-, and third-degree), bradycardia, bundle-branch block, heart failure, hypotension, palpitations, peripheral edema, PVCs, sinus arrest, sinus tachycardia, 12-lead electrocardiogram abnormalities, ventricular fibrillation, ventricular tachycardia
Eyes, Ears, Nose, And Throat: Amblyopia, dry mouth, epistaxis, eye irritation, gingival bleeding and hyperplasia, gingivitis, nasal congestion, retinopathy, taste perversion, tinnitus
Endocrine: Hyperglycemia
Gastrointestinal: Anorexia, constipation, diarrhea, elevated liver function test results, indigestion, nausea, thirst, vomiting
Genitourinary: Acute renal failure, impotence, nocturia, polyuria, sexual dysfunction
Hematologic: Hemolytic anemia, leukopenia, prolonged bleeding time, thrombocytopenia
Musculoskeletal: Arthralgia, muscle spasms, myalgia
Respiratory: Cough, dyspnea
Skin: Alopecia, diaphoresis, erythema multiforme, exfoliative dermatitis, flushing, leukocytoclastic vasculitis, petechiae, photo-sensitivity, pruritus, purpura, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Other: Angioedema, hyperuricemia, weight gain
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Diltiazem
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
The United States Pharmacopeia 31, 2008: Diltiazem Hydrochloride Extended-release Capsules; Diltiazem Hydrochloride Oral Solution; Diltiazem Hydrochloride Oral Suspension; Diltiazem Hydrochloride Tablets.
Proprietary Preparations
Argentina: Acalix; Corodrox; Dilahim; Diltenk; Diltiacor; Dilzen-G; Hart; Incoril; Kaltiazem; Ritmocit; Tilazem;
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Belgium: Progor; Tildiem;
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