Ceftin (Cefuroxime) - Antibiotics
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Ceftin (Cefuroxime)

$113.94


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Ceftin (Cefuroxime)

Class and Category of Drug

Before you buy Ceftin (Cefuroxime) online, read common information about the medication.

Chemical class: Second-generation cephalo-sporin, 7-aminocephalosporanic acid

Therapeutic class: Antibiotic

Pregnancy category: B

Drug Indications and Dosages

Before purchase Ceftin (Cefuroxime) online , you must read how it works.

To treat pharyngitis and tonsillitis

Oral Suspension

Children ages 3 months to 12 years. 10 mg/kg daily in equally divided doses b.i.d. for 10 days. Maximum: 500 mg daily.

Tablets

Adults and children age 13 and over.250 mg b.i.d. for 10 days.

Children under age 13 who can swallow tablets. 125 mg b.i.d. for 10 days.

To treat acute otitis media

Oral Suspension

Children ages 3 months to 12 years.30 mg/kg daily in equally divided doses b.i.d. for 10 days. Maximum: 1,000 mg daily.

Tablets

Children under age 13 who can swallow tablets. 250 mg b.i.d. for 10 days.

To treat impetigo

Oral Suspension

Neonates up to age 1 month. 33.3 to 50 mg/kg every 8 to 12 hr.

Dosage Adjustment

Parenteral dosage reduced to 0.75 g every 12 hr if creatinine clearance is 10 to 20 ml/min/1.73 m2 or to 0.75 g every 24 hr if creatinine clearance less than 10 ml/min/1.73 m2.

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Incompatibilities

Don't admix parenteral cefuroxime with other antibiotics, such as aminoglycosides, because of potential for incompatibility, such as substantial mutual inactivation. If they're administered concurrently, don't mix them in the same intravenous bag or bottle.

Contraindications of Drug

Read contraindications if you want cheap Ceftin (Cefuroxime) online.

Hypersensitivity to cephalosporins or their components

Generic Drug Interactions

Drugs

aminoglycosides, loop diuretics: Increased risk of nephrotoxicity

antacids, H2-receptor antagonists, omeprazole: Decreased cefuroxime axetil absorption probenecid: Increased and prolonged blood cefuroxime level

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Drugs Adverse Reactions

Central Nervous System: Chills, fever, headache, seizures

Cardiovascular: Edema

Eyes, Ears, Nose, And Throat: Hearing loss, oral candidiasis

Gastrointestinal: Abdominal cramps, diarrhea, elevated liver function test results, hepatic failure, hepatomegaly, nausea, pseudomembranous colitis, vomiting

Genitourinary: Elevated BUN level, nephrotoxicity, renal failure, vaginal candidiasis

Hematologic: Eosinophilia, hemolytic anemia, hypoprothrombinemia, neutropenia, thrombocytopenia, unusual bleeding

Musculoskeletal: Arthralgia

Respiratory: Dyspnea

Skin: Ecchymosis, erythema, erythema multiforme, pruritus, rash, Stevens-Johnson syndrome

Other: Anaphylaxis; injection site edema, pain, and redness; superinfection

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Nursing Considerations for Generic Drugs

• Use cefuroxime cautiously in patients hypersensitive to penicillin because cross-sensitivity has occurred in about 10% of such patients.

• If possible, obtain culture and sensitivity results, as ordered, before giving drug.

• Give oral form with food to decrease gastrointestinal distress, as needed.

• Remember that oral forms — tablets and suspension — aren't bioequivalent.

• For intravenous use, reconstitute using manufacturer's instructions according to type of preparation available. Solution ranges in color from light yellow to amber.

• For intramuscular use, add 3 or 3.6 ml sterile water for injection to each 750-mg vial to yield 220 mg/ml.

• If using a container of frozen parenteral solution, thaw at room temperature or under refrigeration before administration; make sure all ice crystals have melted. Don't force thawing by microwaving.

• Store reconstituted parenteral drug for up to 24 hours at room temperature or 96 hours in refrigerator. (Thawed solutions may be stable 24 hours at room temperature or 28 days if refrigerated.) Store reconstituted oral suspension in refrigerator or at room temperature up to 10 days.

• Give intravenous injection over 3 to 5 minutes through tubing of a flowing compatible intravenous fluid.

• Monitor intravenous site for extravasation and phlebitis.

• Monitor BUN and serum creatinine levels and fluid intake and output to detect signs of nephrotoxicity. Monitor patients with renal impairment closely because they may have greater toxic reactions to cefuroxime.

• Monitor patient for allergic reactions continuing up to a few days after therapy starts. Patients with a history of some form of allergy, especially to drugs, are at increased risk for an allergic reaction.

• Assess bowel pattern daily; severe diarrhea may indicate pseudomembranous colitis. If it's suspected, stop drug, as ordered, and provide treatment as prescribed.

• Assess patient for pharyngitis, ecchymosis, bleeding, and arthralgia, which may indicate a blood dyscrasia.

• Monitor prothrombin time and bleeding time, as ordered. Be prepared to administer vitamin K, if ordered, to treat hypothrombinemia.

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Cefuroxime

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


British Pharmacopoeia, 2008 edition: Cefuroxime Axetil Tablets; Cefuroxime Injection;
The United States Pharmacopeia 31, 2008: Cefuroxime Axetil for Oral Suspension; Cefuroxime Axetil Tablets; Cefuroxime for Injection; Cefuroxime Injection.

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