Cephalexin (Keftab)
Class and Category of Drug
Before you buy Cephalexin (Keftab) online, read common information about the medication.
Chemical class: First-generation cephalosporin, 7-aminocephalosporanic acid
Therapeutic class: Antibiotic
Pregnancy category: B
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Drug Indications and Dosages
Before purchase Cephalexin (Keftab) online , you must read how it works.
To treat streptococcal tonsillitis, pharyngitis, and skin and soft-tissue infections
Capsules, Oral Suspension, Tablets
Adults and adolescents age 15 and over. 500 mg every 12 hr. Maximum: 4 g daily.
Children and adolescents ages 2 to 15.25 to 50 mg/kg daily divided into two equal doses and given every 12 hr. If infection is severe, dose may be doubled.
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Generic Drug Mechanism of Action
Like all cephalosporins, cephalexin interferes with bacterial cell wall synthesis by inhibiting the final step in the cross-linking of peptidoglycan strands. Peptidoglycan makes the cell membrane rigid and protective. Without it, bacterial cells rupture and die. This mechanism of action is most effective against bacteria that divide rapidly, including many gram-positive and gram-negative bacteria.
To treat mild to moderate respiratory tract, skin, soft-tissue, bone, and genitourinary infections caused by susceptible organisms other than streptococci
Capsules, Oral Suspension, Tablets
Adults. 250 mg every 6 hr.
Oral Suspension
Children. 25 to 50 mg/kg daily in equally divided doses b.i.d. or q.i.d.
To treat severe respiratory tract, skin, soft-tissue, bone, and genitourinary infections
Capsules, Oral Suspension, Tablets
Adults. 0.5 to 1 g every 6 hr. Maximum: 4 g daily.
Children. 50 to 100 mg/kg daily in equally divided doses q.i.d.
To treat otitis media
Oral Suspension
Children. 75 to 100 mg/kg daily in equally divided doses q.i.d.
To treat uncomplicated cystitis
Capsules, Oral Suspension, Tablets
Adults and adolescents age 15 and over. 500 mg every 12 hr.
Contraindications of Drug
Read contraindications if you want cheap Cephalexin (Keftab) online.
Hypersensitivity to cephalosporins or their components
Generic Drug Interactions
Drugs
aminoglycosides, loop diuretics: Increased risk of nephrotoxicity
probenecid: Increased and prolonged blood cephalexin level
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Drugs Adverse Reactions
Central Nervous System: Chills, fever, headache, seizures
Cardiovascular: Edema
Eyes, Ears, Nose, And Throat: Hearing loss
Gastrointestinal: Abdominal cramps, diarrhea, elevated liver function test results, hepatic failure, hepatomegaly, nausea, oral candidiasis, pseudomembranous colitis, vomiting
Genitourinary: Elevated BUN level, nephrotoxicity, renal failure, vaginal candidiasis
Hematologic: Eosinophilia, hemolytic anemia, hypoprothrombinemia, neutropenia, thrombocytopenia, unusual bleeding
Musculoskeletal: Arthralgia
Respiratory: Dyspnea
Skin: Ecchymosis, erythema, erythema multiforme, pruritus, rash, Stevens-Johnson syndrome
Other: Anaphylaxis, superinfection
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Nursing Considerations for Generic Drugs
• Use cephalexin cautiously in patients hypersensitive to penicillin because cross-sensitivity occurs in about 10% of them.
• If possible, obtain culture and sensitivity test results, as ordered, before giving drug.
• Monitor patient's BUN and serum creatinine levels to detect early signs of nephrotoxicity. Also monitor fluid intake and output; decreasing urine output may indicate nephrotoxicity.
• Monitor for allergic reactions a few days after therapy starts.
• Assess CBC, hematocrit, and serum aspartate aminotransferase, alanine aminotransferase, bilirubin, LD, and alkaline phosphatase levels during long-term therapy.
• Assess patient's bowel pattern daily; severe diarrhea may indicate pseudomembranous colitis caused by Clostridium difficile. If diarrhea occurs, notify prescriber and expect to withhold cefotaxime and treat with fluids, electrolytes, protein, and an antibiotic effective against C. difficile.
• Assess patient for pharyngitis, ecchymosis, bleeding, and arthralgia; they may indicate a blood dyscrasia.
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