Diamox (Acetazolamide)
Class and Category of Drug
Before you buy Diamox (Acetazolamide) online, read common information about the medication.
Chemical class: Sulfonamide derivative
Therapeutic class: Anticonvulsant, anti-glaucoma, diuretic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Diamox (Acetazolamide) online , you must read how it works.
To treat chronic simple (open-angle) glaucoma
Sustained-Release Capsules, Tablets, Intravenous or Intramuscular Injection
Adults. 250 to 1,000 mg daily (divided for doses exceeding 250 mg).
As short-term therapy to treat secondary glaucoma and preoperatively to treat acute congestive (closed-angle) glaucoma
Sustained-Release Capsules, Tablets, Intravenous or Intramuscular Injection
Adults. 250 mg b.i.d. or every 4 hr; or 1 Sustained-Release capsule (500 mg) b.i.d.; or 500 mg initially, followed by 125 to 250 mg every 4 to 6 hr for severe acute glaucoma. To initially lower intraocular pressure rapidly, 500 mg I.V.; may repeat in 2 to 4 hr in acute cases, depending on patient response. Oral therapy usually started after initial intravenous dose.
Sustained-Release Capsules, Tablets
Children. 10 to 15 mg/kg daily in divided doses every 6 to 8 hr.
Intravenous or Intramuscular Injection
Children. 5 to 10 mg/kg/dose every 6 hr.
To induce diuresis in heart failure
Tablets, Intravenous or Intramuscular Injection
Adults. Initial: 250 to 375 mg or 5 mg/kg daily in morning. Maintenance: 250 to 375 mg or 5 mg/kg on alternate days or for 2 days followed by a drug-free day.
To treat drug-induced edema
Tablets, Intravenous or Intramuscular Injection
Adults. 250 to 375 mg daily for 1 to 2 days.
Tablets, Intravenous Injection
Children. 5 mg/kg/dose daily in morning.
To treat seizures, including generalized tonic-clonic, absence, and mixed seizures, and myoclonic jerk patterns
Tablets, Intravenous or Intramuscular Injection
Adults and children. 8 to 30 mg/kg daily in divided doses. Optimal: 375 to 1,000 mg daily. When used with other anticonvulsants, 250 mg daily.
To prevent or relieve symptoms of acute mountain sickness
Sustained-Release Capsules, Tablets
Adults. 500 to 1,000 mg daily in divided doses, given 24 to 48 hr before ascent and continued for 48 hr or longer while at high altitude p.r.n. to control symptoms.
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Contraindications of Drug
Read contraindications if you want cheap Diamox (Acetazolamide) online.
Chronic noncongestive closed-angle glaucoma; cirrhosis; hyperchloremic acidosis; hypersensitivity to acetazolamide; hypokalemia; hyponatremia; severe pulmonary obstruction; severe renal, hepatic, or adrenocortical impairment
Generic Drug Interactions
Drugs
amphetamines, methenamine, phenobarbital, procainamide, quinidine: Decreased excretion and possibly toxicity of these drugs
corticosteroids: Increased risk of hypokalemia
cyclosporine: Increased cyclosporine level, possibly nephrotoxicity or neurotoxicity
diflunisal: Possibly significantly decreased intraocular pressure
lithium: Increased excretion and decreased effectiveness of lithium
primidone: Decreased serum and urine primidone levels
salicyhtes: Increased risk of salicylate toxicity
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Drugs Adverse Reactions
Central Nervous System: Ataxia, confusion, depression, disorientation, dizziness, drowsiness, fatigue, fever, flaccid paralysis, headache, lassitude, malaise, nervousness, paresthesia, seizures, tremor, weakness
Eyes, Ears, Nose, And Throat: Altered taste, tinnitus, transient myopia
Gastrointestinal: Anorexia, constipation, diarrhea, hepatic dysfunction, melena, nausea, vomiting
Genitourinary: Crystalluria, decreased libido, glycosuria, hematuria, impotence, nephrotoxicity, phosphaturia, polyuria, renal calculi, renal colic, urinary frequency
Hematologic: Agranulocytosis, hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia, thrombocytopenic purpura
Skin: Photosensitivity, pruritus, rash, Stevens-Johnson syndrome, urticaria
Other: Acidosis, hyperuricemia, hypokalemia, weight loss
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Nursing Considerations for Generic Drugs
• Use acetazolamide cautiously in patients with calcium-based renal calculi, diabetes mellitus, gout, or respiratory impairment.
• Know that acetazolamide may increase risk of hepatic encephalopathy in patients with hepatic cirrhosis.
• To avoid painful intramuscular injections (caused by alkaline solution), give acetazolamide by mouth or intravenous injection if possible.
• Reconstitute each 500-mg vial with at least 5 ml sterile water for injection. Use within 24 hours because drug has no preservative.
• Monitor blood tests during acetazolamide therapy to detect electrolyte imbalances.
• Monitor fluid intake and output every 8 hours and body weight daily to detect excessive fluid and weight loss.
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Acetazolamide
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
British Pharmacopoeia, 2008 edition: Acetazolamide Tablets;
The United States Pharmacopeia 31, 2008: Acetazolamide for Injection; Acetazolamide Tablets.
Proprietary Preparations
Argentina: Diamox;
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