Didronel (Etidronate)
Class and Category of Drug
Before you buy Didronel (Etidronate) online, read common information about the medication.
Chemical class: Bisphosphonate
Therapeutic class: Antihypercalcemic agent, bone resorption inhibitor
Pregnancy category: B (oral), C (parenteral)
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Drug Indications and Dosages
Before purchase Didronel (Etidronate) online , you must read how it works.
To treat Paget's disease of bone (osteitis deformans)
Tablets
Adults. 5 to 10 mg/kg daily for up to 6 mo, or 11 to 20 mg/kg daily for up to 3 mo.
To prevent and treat heterotopic ossification after total hip replacement
Tablets
Adults. 20 mg/kg daily for 1 mo before surgery and then 20 mg/kg daily for 3 mo after surgery for a total of 4 mo of treatment.
To prevent and treat heterotopic ossification after spinal cord injury
Tablets
Adults. 20 mg/kg daily for 2 wk and then 10 mg/kg daily for 10 wk for a total of 12 wk of treatment.
To treat moderate to severe hypercalcemia caused by cancer
Intravenous Infusion
Adults. Initial: 7.5 mg/kg daily infused over at least 2 hr for 3 to 7 successive days. Oral etidronate may begin at 20 mg/kg/day for 30 days on the day after last infusion.
Dosage Adjustment Dosage reduced in renal impairment. Drug not given if serum creatinine level exceeds 5 mg/dl.
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Contraindications of Drug
Read contraindications if you want cheap Didronel (Etidronate) online.
Esophageal abnormalities that delay gastric emptying, such as achalasia and stricture; hypersensitivity to etidronate, bisphosphonates, or their components; severe renal impairment
Generic Drug Interactions
Drugs
antacids that contain aluminum, calcium, or magnesium; vitamin and mineral supplements that contain aluminum, calcium, iron, or magnesium: Decreased etidronate absorption
Foods
high-calcium food (such as milk and other dairy products): Decreased etidronate absorption
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Drugs Adverse Reactions
Eyes, Ears, Nose, And Throat: Altered taste, metallic taste
Gastrointestinal: Diarrhea, elevated liver function test results, nausea
Genitourinary: Nephrotoxicity
Musculoskeletal: Bone fractures, bone pain, osteonecrosis of jaw
Other: Hypocalcemia
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Nursing Considerations for Generic Drugs
• Use etidronate cautiously in patients with upper gastrointestinal problems such as Barrett's esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis, or ulcers because drug may cause local irritation of the upper gastrointestinal mucosa.
• Anticipate starting etidronate as soon as possible after spinal cord injury, preferably before signs of heterotopic ossification.
• Expect etidronate not to inhibit healing of spinal fractures, affect prosthesis, or disrupt trochanter attachment when used after total hip replacement.
• Give oral form 2 hours before meals to prevent decreased absorption.
• Dilute parenteral form in at least 250 ml of normal saline solution.
• Give parenteral form slowly over at least 2 hours.
• Store diluted parenteral solution at room temperature for up to 48 hours.
WARNING Watch for hypocalcemia if patient receives parenteral form for more than 3 days.
• When treating hypercalcemia, expect to continue giving drug for up to 90 days if serum calcium level remains within acceptable range.
• Monitor patient for adverse esophageal effects such as esophagitis, esophageal ulcers, and esophageal erosions that may occur with bleeding, as well as gastric and duodenal ulcers, because these adverse effects have occurred with other oral biphosphonates.
• Risk of severe adverse esophageal reactions increases in patients who lie down after taking drug, who fail to swallow it with a full glass of water, or who continue to take drug after developing symptoms of esophageal irritation.
• Make sure patient has had a dental checkup before having an invasive dental procedures during etidronate therapy, especially if he has cancer; is receiving chemotherapy, head or neck radiation, or a corticosteroid; or has poor oral hygiene because the risk of osteonecrosis is increased in these patients.
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Etidronate
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
The United States Pharmacopeia 31, 2008: Etidronate Disodium Tablets.
Proprietary Preparations
Argentina: Difosfen;
Australia: Didronel;
Austria: Detidron; Didronel;
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Belgium: Didronel; Osteodidronel;
Canada: Didronel;
The pharmaceutical companies our pharmacies buy from follow strict WHO standards for GMP.
Chile: Osteotop;
Denmark: Didronate;
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Finland: Didronate;
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France: Didronel;
Germany: Didronel; Diphos; Etidron;
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Greece: Anfozan; Biotredine; Dralen; Etidron; Etiplus; Feminoflex; Maxibral; Oflocin; Osfo; Ostedron; Osteodrug; Osteoton; Ostogene; Ostopor; Somaflex; Sterodome; Sviroxit; Tilferan;
Hong Kong: Didronel;
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India: Dronate-OS;
Ireland: Didronel; Israel: Didronel;
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Italy: Didronel; Etidron;
Japan: Didronel;
Netherlands or Holland: Didronel;
New Zealand: Didronel; Etidrate;
Poland: Ostedron;
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Portugal: Didronel;
Singapore: Difosfen;
Spain: Difosfen; Osteum;
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Sweden: Didronate; Etidrel;
Switzerland: Didronel;
Thailand: Difosfen;
Turkey: Didronat;
UK or Britain: Didronel;
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US or USA: Didronel.
Multi-ingredient
Argentina: Emoform Total; Squam;
Australia: Didrocal;
Canada: Didrocal;
Denmark: Didronate Calcium;
Our Drug Store source all of the medicines from India, the world’s largest manufacturer of generic drugs.
Finland: Didronate + Calcium;
Germany: Didronel Kit; Etidron Kombi;
Ireland: Didronel PMO;
Netherlands or Holland: Didrokit;
Norway: Didronate + Calsium;
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Sweden: Didronate + Calcium; Etidrel Kit;
UK or Britain: Didronel PMO; Tiloetca Combi.
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No. You can buy Didronel (Etidronate) without a prescription!
