Ethionamide (Trecator-SC) - Antibiotics
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Ethionamide (Trecator-SC)

$52.11


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Ethionamide (Trecator-SC)

Class and Category of Drug

Before you buy Ethionamide (Trecator-SC) online, read common information about the medication.

Chemical class: Thiamide analogue of isonicotinic acid

Therapeutic class: Antituberculotic

Pregnancy category: Not rated

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Drug Indications and Dosages

Before purchase Ethionamide (Trecator-SC) online , you must read how it works.

As adjunct to treat tuberculosis

Tablets

Adults. 0.5 to 1 g daily in divided doses every 8 to 12 hr, together with other antitu-berculotics. Maximum: 1 g daily.

Children. 15 to 20 mg/kg daily in divided doses every 8 to 12 hr, together with other antituberculotics. Maximum: 750 mg daily.

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Contraindications of Drug

Read contraindications if you want cheap Ethionamide (Trecator-SC) online.

Hypersensitivity to ethionamide or its components, severe hepatic damage

Generic Drug Interactions

Drugs

cycloserine: Increased risk of adverse CNS effects, especially seizures

other neurotoxic drugs: Increased risk of neurotoxicity, such as optic and peripheral neuritis

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Drugs Adverse Reactions

Central Nervous System: Burning or pain in arms and legs, clumsiness, confusion, depression, mental or mood changes, paresthesia, unsteadiness

Cardiovascular: Orthostatic hypotension

Eyes, Ears, Nose, And Throat: Blurred vision, eye pain, increased salivation, metallic taste, optic neuritis, stomatitis, vision loss

Endocrine: Goiter, hypoglycemia, hypothyroidism

Gastrointestinal: Anorexia, hepatitis, nausea, vomiting

Skin: Jaundice, rash

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Nursing Considerations for Generic Drugs

• Use ethionamide cautiously in patients with a history of hypersensitivity to isoniazid, niacin, pyrazinamide, or chemically related drugs; these ptients also may be hypersensitive to ethionamide.

• Expect to give another antituberculotic with ethionamide to decrease the risk of development of bacterial resistance.

• Also plan to give pyridoxine to prevent or minimize peripheral neuritis (burning, numbness, pain, or tingling in hands and feet), especially if patient has already had isoniazid-induced peripheral neuritis.

• Monitor liver function test results, and assess for signs of impaired function, such as hepatitis and jaundice.

• Question patient regularly about vision changes. Notify prescriber about blurred vision, eye pain, or loss of vision or acuity.

• Monitor compliance; treatment may need to continue for 1 to 2 years or indefinitely.

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