ibuprofen
Actiprofen Caplets (CAN), Advil, Apo-Ibuprofen (CAN), Bayer Select Ibuprofen Pain Relief Formula Caplets, Caldolor, Children's Advil, Children's Motrin, Dolgesic, Excedrin IB, Genpril, Haltran, Ibifon 600 Caplets, Ibuprin, Ibuprohm Caplets, Ibu-Tab, Medipren, Midol IB, Motrin, Motrin-IB, Novo-Profen (CAN), Nu-Ibuprofen (CAN), Nuprin, Pamprin-IB, Q-Profen, Rufen, Trendar
Class and Category of Drug
Chemical class: Propionic acid derivative
Therapeutic class: Analgesic, anti-inflammatory, antipyretic
Pregnancy category: C (before 30 weeks gestation); D (starting at 30 weeks gestation)
Quick delivery, overnight shipping and Saturday delivery options are also available.
Drug Indications and Dosages
To relieve pain in rheumatoid arthritis and osteoarthritis
Capsules, Chewable Tablets, Oral Suspension, Tablets
Adults. 300 mg q.i.d., or 400, 600, or 800 mg t.i.d. or q.i.d. Range: 1.2 to 3.2 g daily.
To relieve mild to moderate pain
Capsules, Chewable Tablets, Oral Suspension, Tablets
Adults. 400 mg every 4 to 6 hr, p.r.n.
Intravenous Infusion
Adults. 400 to 800 mg infused over at least 30 minutes, every 6 hours, as needed.
To relieve acute migraine pain
Capsules, Chewable Tablets, Oral Suspension, Tablets
Adults. 200 to 400 mg at onset of migraine
pain. Maximum: 400 mg daily.
To relieve pain in primary dysmenorrhea
Capsules, Chewable Tablets, Oral Suspension, Tablets
Adults. 400 mg every 4 hr, p.r.n.
To relieve pain in juvenile arthritis
Capsules, Chewable Tablets, Oral Suspension, Tablets
Children. 30 to 70 mg/kg daily in divided doses t.i.d. or q.i.d.; 20 mg/kg daily for mild of days!
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To relieve minor aches, pains, and dysmenorrhea and to reduce fever
Capsules, Chewable Tablets, Oral Suspension, Tablets
Adults. 200 to 400 mg every 4 to 6 hr. Maximum: 1.2 g daily.
To relieve moderate to severe pain as an adjunct to opioid analgesics
Intravenous Infusion
Adults. 400 mg to 800 mg infused over at least 30 minutes, every 6 hours, as needed.
To reduce fever
Capsules, Chewable Tablets, Oral Suspension, Tablets
Children ages 6 months to 12 years.5 to 10 mg/kg every 4 to 6 hr. Maximum: 40 mg/ kg daily.
Intravenous Infusion
Adults. 400 mg infused over at least 30 minutes, followed by 400 mg infused over at least 30 minutes, every 4 to 6 hours. Or, 100 to 200 mg infused over at least 30 minutes, every 4 hours, as needed.
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Contraindications of Drug
Angioedema, asthma, bronchospasm, nasal polyps, rhinitis, or urticaria caused by hypersensitivity to aspirin, ibuprofen, iodides, or other NSAIDs; perioperative pain with coronary artery bypass graft surgery
Generic Drug Interactions
Drugs
acetaminophen: Possibly increased renal effects with long-term use of both drugs antihypertensives: Decreased effectiveness of these drugs
aspirin: Possibly decreased cardioprotective and stroke-preventive effects of aspirin
aspirin, other NSAIDs: Increased risk of bleeding and adverse gastrointestinal effects bone marrow depressants: Possibly increased leukopenic and thrombocytopenic effects of bone marrow depressants
cefamandole, cefoperazone, cefotetan: Increased risk of hypoprothrombinemia and bleeding
colchicine, platelet aggregation inhibitors: Increased risk of gastrointestinal bleeding, hemorrhage, and ulcers
corticosteroids, potassium supplements: Increased risk of adverse gastrointestinal effects
cyclosporine: Increased risk of nephrotoxicity from both drugs, increased blood cyclosporine level
digoxin: Increased blood digoxin level and risk of digitalis toxicity
diuretics (loop, potassium-sparing, and thiazide): Decreased diuretic and antihypertensive effects
gold compounds, nephrotoxic drugs: Increased risk of adverse renal effects heparin, oral anticoagulants, thrombolytics: Increased anticoagulant effects, increased risk of hemorrhage
insulin, oral antidiabetics: Possibly increased hypoglycemic effects of these drugs lithium: Increased blood lithium level
methotrexate: Decreased methotrexate clearance and increased risk of toxicity plicamycin, valproic acid: Increased risk of hypoprothrombinemia and gastrointestinal bleeding, hemorrhage, and ulcers
probenecid: Possibly increased blood level, effectiveness, and risk of toxicity of ibuprofen
Activities
alcohol use: Increased risk of adverse gastrointestinal effects
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Drugs Adverse Reactions
Central Nervous System: Aseptic meningitis, dizziness, headache, nervousness, seizures, stroke
Cardiovascular: Fluid retention, heart failure, hypertension, MI, peripheral edema, tachycardia
Eyes, Ears, Nose, And Throat: Amblyopia, epistaxis, stomatitis, tinnitus
Gastrointestinal: Abdominal cramps, distention, or pain; anorexia; constipation; diarrhea; diverticulitis; dyspepsia; dysphagia; elevated liver function test results; epigastric discomfort; esophagitis; flatulence; gastritis; gastroenteritis; gastroesophageal reflux disease; gastrointestinal bleeding, hemorrhage, perforation, or ulceration; heartburn; hemorrhoids; hepatic failure; hepatitis; hiatal hernia; indigestion; melena; nausea; stomatitis; vomiting
Genitourinary: Cystitis, hematuria, renal failure (acute)
Hematologic: Agranulocytosis, anemia, aplastic anemia, eosinophilia, hemolytic anemia, leukopenia, neutropenia, pancytopenia, prolonged bleeding time, thrombocytopenia
Respiratory: Bronchospasm, dyspnea, wheezing
Skin: Blisters, erythema multiforme, photosensitivity, pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Other: Anaphylaxis, angioedema, flulike symptoms, hypokalemia, weight gain
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Nursing Considerations for Generic Drugs
• Use ibuprofen with extreme caution in patients with a history of ulcer disease or gastrointestinal bleeding because NSAIDs such as ibuprofen increase risk of gastrointestinal bleeding and ulceration. Expect to use ibuprofen for shortest time possible in these patients.
• Risk of serious cardiovascular thrombotic events such as a MI or stroke increases the longer ibuprofen is used. Expect to give drug for shortest time possible.
• For intravenous use, dilute Caldolor brand of ibuprofen to final concentration of 4 mg/ ml or less using 0.9% sodium chloride injection, 5% dextrose injection, or lactated Ringer's solution. For an 800-mg dose, dilute 8 ml Caldolor in at least 200 ml diluent; for a 400-mg dose, dilute 4 ml Caldolor in at least 100 ml diluent. Diluted solutions may be kept at room temperature up to 24 hours. When infusing ibuprofen intravenously, infusion time must be at least 30 minutes.
• Serious gastrointestinal tract ulceration, bleeding, and perforation may occur without warning symptoms. Elderly patients are at greater risk. To minimize risk, give oral drug with food. If gastrointestinal distress occurs, withhold drug and notify prescriber immediately.
• Use ibuprofen cautiously in patients with hypertension, and monitor blood pressure closely throughout therapy. Drug may cause hypertension or worsen it.
WARNING Monitor patient closely for thrombotic events, including MI and stroke, because NSAIDs increase the risk.
• Monitor patient — especially if he's elderly or receiving long-term oral ibuprofen therapy — for less common but serious adverse gastrointestinal reactions, including anorexia, constipation, diverticulitis, dysphagia, esophagitis, gastritis, gastroenteritis, gastroesophageal reflux disease, hemorrhoids, hiatal hernia, melena, stomatitis, and vomiting.
• Monitor liver function test results because, in rare cases, elevations may progress to severe hepatic reactions, including fatal hepatitis, liver necrosis, and hepatic failure.
• Monitor BUN and serum creatinine levels in elderly patients, patients taking diuretics or ACE inhibitors, and patients with heart failure, impaired renal function, or hepatic dysfunction; drug may cause renal failure.
• Monitor CBC for decreased hemoglobin and hematocrit. Drug may worsen anemia.
WARNING If patient has bone marrow suppression or is receiving an antineoplastic drug, monitor laboratory results (including WBC count), and watch for evidence of infection. Ibuprofen's anti-inflammatory and antipyretic actions may mask signs and symptoms, such as fever and pain.
• Assess patient's skin regularly for signs of rash or other hypersensitivity reaction because ibuprofen is an NSAID and may cause serious skin reactions without warning, even in patients with no history of NSAID sensivitity. At first sign of reaction, stop drug and notify prescriber.
• Although analgesic effect occurs at low doses, expect to give at least 400 mg four times daily for anti-inflammatory effect.
• Expect higher doses for rheumatoid arthritis than for osteoarthritis.
• Be aware that ibuprofen oral suspension may contain sucrose, which may affect blood glucose level in diabetic patients.
Ibuprofen
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
British Pharmacopoeia, 2008 edition: Ibuprofen Cream; Ibuprofen Gel; Ibuprofen Oral Suspension; Ibuprofen Tablets;
The United States Pharmacopeia 31, 2008: Ibuprofen and Pseudoephedrine Hydrochloride Tablets; Ibuprofen Oral Suspension; Ibuprofen Tablets.
Proprietary Preparations
Argentina: Actron; Acuilfem; Afebril; Algioprofen; Atomo Desinflamante Ibu; Bistryl; Brunal; Butidiona; Causalon Ibu; Copiron; Dolocox; Dolorsyn; Druisel; Fabogesic; Febratic; Fontol; Ibu; Ibu Evanol; Ibu-Lady; Ibu-Novalgina; Ibubenitol; Ibucalmin; Ibucler; Ibufabra; Ibufix; Ibulam; Ibumar; Ibumultin; Ibup; Ibupirac; Ibupiretas; Ibuprofenix; Ibuprofex; Ibusi; Ibusol; Ibusumal; Ibutenk; Ibuxim; Ibuzidine; Kesan; Matrix; Motrax; Novo Geniol; Oxibut; Pakurat; Paraflex Crema; Ponstil Mujer; Ponstin; Ponstinetas; Salivia; Sindol; Teprix; Tonal; Vefren;
Australia: ACT-3; Actiprofen; Advil; Brufen; Bugesic; Dimetapp Pain & Fever Relief; Hexal Compufen; Nurofen; Proven; Rafen; Tri-Profen;
Austria: Advil; Aktren; Avallone; Brufen; Dismenol Neu; Dolgit; Dolibu; Dolofort; Duafen; Ibu; Ibudol; Ibufem; Ibugel; Ibumetin; Ibupron; Iburem; Ibutop; Imbun; Kratalgin; Momento; Nurofen; ratioDolor; Tabcin; Urem;
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Belgium: Adulfen Lysine; Advil Mono; Brufen; Buprophar; Dolofin; Epsilon; Extrapan; Ibu-Slow; Ibumed; Ibutop; Junifen; Malafene; Nurofebryl; Nurofen; Optalidon Nieuwe Formule; Perdofemina; Perdophen; Perviam; Provenol; Siprofen; Spidifen;
Brazil: Actiprofen; Advil; Algiflex; Algy-Flanderil; Alivium; Artril; Dalsy; Doraplax; Doretrim; Dorigren; Frenador; Ib-Profeno; Ibufran; Ibupril; Ibuprofan; Lombalgina; Motrin; Parartrin; Spidufen; Uniprofen;
Canada: Advil; Motrin; Novo-Profen;
The pharmaceutical companies our pharmacies buy from follow strict WHO standards for GMP.
Chile: Actron; Advil; Bediatil; Bladex; Deucodol; Dolorub; Fenpic; Fortapal; Ibu; Ibu-4; Ibu-6; Ibupirac; Ipson; Kin; Motrin; Niofen; Pediaprofen; Pironal; Pyriped; Tifen;
Czech Republic: Advil; Baroc; Brufen; Dolgit; Ibalgin; Ibumax; Irfen; Nurofen; Nurofen Advance; Nurofen Stopgrip; Pabiprofen; Panafen; Pedea; Solpaflex; Tomaflex; Urgo;
Denmark: Apain; Brufen; Ibumetin; Ibureumin; Ibutop; Ipren; Pedea; Solpaflex;
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Finland: Brufen; Burana; Ibumax; Ibumetin; Ibusal; Ibuxin;
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France: Advil; Anadvil; Antarene; Brufen; Dolgit; Doltaque; Ergix; Expanfen; Gelufene; Hemagene Tailleur; Ibualgic; Ibutop; Intralgis; Nureflex; Nurofen; Nurofentabs; Nuroflash; Pedea; Solufen; Spedifen; Spifen; Upfen;
Germany: Advel; Aktren; Contraneural; Dismenol N; Dolgit; Dolo Sanol; Dolo-Puren; Dolodoc; Dolormin; Esprenit; Eudorlin Extra; Eudorlin Migrane; Gyno-Neuralgin; Gynofug; Ibu; Ibu Benuron; ibu-Attritin; Ibu-ratiopharm; Ibubeta; Ibudolor; Ibuflam; Ibuhexal; Ibumerck; Ibuphlogont; Ibuprof; Ibutad; Ibutop; Ilvico grippal; Imbun; Jenaprofen; Kontagripp; Mensoton; Migranin Ibuprofen; Novogent; Nurofen; Optalidon; Opturem; Parsal; Pedea; Pfeil; Phamoprofen; ratioDolor; Schmerz-Dolgit; Spalt; Tabalon; Tempil; Tispol Ibu-DD; Togal Akut Ibuprofen; Trauma-Dolgit; Urem;
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Greece: Advil; Algofren; Brufen; Buscofem; Nurofen; Rozovin;
Hong Kong: Advil; Bifen; Brufen; Bupogesic; Dolo-Spedifen; Ibufac; Ibupen; Neutropain; Nurofen; Perofen; Profen; Rupan; Schufen; Spedifen;
Hungary: Advil; Algoflex; Dolgit; Huma-Profen; Ibulos; Ibumax; Ibutop; Melfen; Nurofen; Solpaflex; Spedifen;
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India: Brufen; Butafen; Cipgesic; Emflam; Ibugesic; Ibupal;
Indonesia: Anafen; Arthrifen; Bufect; Dofen; Dolofen-F; Febryn; Fenris; Iprox; Lexaprofen; Nofena; Ostarin; Prifen; Profen; Proris; Rhelafen; Ribunal; Shelrofen; Spedifen; Yariven;
Ireland: Advil; Brufen; Bufigen; Fenopine; Ibugel; Melfen; Nurofen; Phorpain; Proflex; Solfen; Israel: Adex; Advil; Artofen; Ibufen; Ibuleve; Nurofen;
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Italy: Algofen; Antalfebal; Antalfort; Antalgil; Antalisin; Arfen; Benflogin; Brufen; Buscofen; Calmine; Cibalgina Due Fast; Dolocyl; Dolofast; Edenil; Faspic; Ganaprofene; Gineflor; Ginenorm; Moment; Nureflex; Nurofast; Nurofen; Nurosolv; Pedea; Subitene; Zafen;
Malaysia: Bifen; Brugesic; Ibufac; Ibufen; Nurofen; Perofen; Rupan; Spedifen;
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Mexico: ABKI; Actron; Adivon; Advil; Aflusil; Ainex; Aldofen; Algidol; Bestafen; Carone; Citalgan; Dadicil; Days; Dibufen; Dipofen; Diprodol; Dolprin; Dolprofen; Dolval; Dolver; Eufenil; Febratic; Fidoin-Q; Flexafen; Gelidol; Gobrosan; Ibuflam; Ibuflex; Ifentil; Inpained; Maxifen; Medifen; Mejorultra; Motrin; Natiken; Novartril; Offeno; Pro-XB; Proartinal; Probuxil; Quadrax; Realdrax; Ribufen; Tabalon;
Netherlands or Holland: Advil; Brufen; Femapirin; Ibosure; Ibulgan; Nurofen; Pedea; Roco; Sarixell; Spidifen; Zafen;
Norway: Brufen; Ibumetin; Ibuprox; Ibux;
New Zealand: ACT-3; Brufen; Fenapaed; Ibucare; Nurofen; Panafen;
Philippines: Advil; Brufen; Dolan; Idyl; Medicol; Midol; Skelan;
Poland: Bolinet; Deep Relief; Dolgit; Ibufen; Ibum; Ibupar; Ibuprom; Nurofen; Pedea;
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Portugal: Anadvil; Arfen; Baroc; Brufen; Calbrun; Dolocyl; Dolomate; Dolormin; Faspic; Frenidor; Ibupax; Junifen; Moment; Motrin; Norvectan; Nuprilan; Nurofen; Ozonol; Pedea; Plusofen; Seclodin; Solufen; Solvium; Spidifen; Sporfen; Trifene; Zafen; Zip-A-Dol;
Russia: Aldospray (Альдоспрей); Burana (Бурана); Dolgit (Долгит); Ibufen (Ибуфен); Nurofen (Нурофен); Solpaflex (Солпафлекс);
South Africa:
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France: Advil; Antiflam; Betagesic; Betaprofen; Brufen; Brugesic; Iboflam; Ibugesic; Ibuleve; Ibumax; Ibumed; Inza; Lenafen; Norflam T; Nurofen; Painil; Ranfen;
Singapore: Ampifen; Bifen; Ibufen; Ibuloid; Nurofen;
Spain: Advil; Aldospray Analgesico; Algiasdin; Algidrin; Alogesia; Altior; Babypiril; Bexistar; Calmafher; Dadosel; Dalsy; Diltix; Doctril; Dolbufen; Dolorac; Dorival; Espidifen; Factopan; Feminalin; Fiedosin; Frenatermin; Gelofeno; Ibubex; Ibufen; Ibumac; Ibuprox; Inadol; Isdibudol; Isdol; Junifen; Narfen; Neobrufen; Nodolfen; Norvectan; Nurofen; Oberdol; Oltyl; Optajun; Paidofebril; Pedea; Pirexin; Pocyl; Ratiodol; Remidol; Saetil; Solvium; Takigrip; Tedifebrin;
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Sweden: Alindrin; Brufen; Ibumetin; Ipren;
Switzerland: Algifor; Artofen; Brufen; Dismenol; Dolo-Dismenol; Dolo-Spedifen; Dolocyl; Ecoprofen; Grefen; Ibufen-L; Ibusifar; Iproben; Iprogel; Irfen; Melabon; Nurofen; Optifen; Perskindol Ibuprofen acute; Saridon N; Sinedol Ibuprofen; Spedifen; Treupel Dolo Ibuprofen;
Thailand: Ambufen; Anbifen; Aprofen; Babefen Sus; Borafen; Borakid; Brufen; Brumed; Bruprin; Brusil; Bumed; Cefen; Cenbufen; Duran; Faspic; G-Fen; Gesica; Greatofen; Heidi; Ibrofen; Ibu; Ibufac; Ibugan; Ibulan; Iburen; Junifen; Mano-Bruzone; Nurofen; Ostofen; P-Fen; Perofen; Pippen; Probue; Probufen; Profena; Profeno; Rheumanox; Rumasian; Rumatifen; Rupan; Schufen; Skelan IB; Tofen; Trofen; Umafen;
Turkey: Advil; Artril; Bebol; Biophen; Brufen; Dolgit; Dolven; Gerofen; Ibu-600; Ibufen; Nurofen; Pedifen; Profen; Repozal; Rofen; Siyafen; Suprafen; Temsofen; Ultrafen; Upren; UAE: Profinal;
UK or Britain: Advil; Anadin Ibuprofen; Anadin Joint Pain; Anadin Ultra; Arthrofen; Biatain-Ibu; Brufen; Calprofen; Cuprofen; Ebufac; Fenbid; Fenpaed; Feverfen; Galprofen; Hedex Ibuprofen; Ibrufhalal; Ibufem; Ibugel; Ibuleve; Ibumousse; Ibuspray; Ibutop Cuprofen; Ibutop Ralgex; Librofem; Mandafen; Manorfen; Mentholatum Ibuprofen; Migrafen; Motrin; Novaprin; Nurofen; Nurofen Migraine; Obifen; Orbifen; Pacifene; Pedea; Phor Pain; Proflex; Radian-B Ibuprofen; Relcofen; Rimafen;
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US or USA: Advil; Anadar; Genpril; Haltran; Ibu; Ibu-Tab; Ibu-4, -6, -8; Ibutab; Menadol; Midol Cramp & Body Aches; Motrin; NeoProfen; Nuprin; Saleto-200;
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Venezuela: Advil; Brugesic; Buprifen; Buprodol; Butilene; Dologesic; Femicaps; Femmex Plus; Ibucaps; Ibufen; Ibufenac; Ibuprin; Ibuprox; Ibutan; Lumbax; Max; Maydol; Mestral; Motrin; Pedibu.
Multi-ingredient
Argentina: Aliviagrip; Bioneural B12; Buscapina Fem; Butidiona; Causalon Gesic; Deep Relief; Dexprofeno; Espasmo Ibupirac; Espasmo Motrax; Espasmofin; Ibu Evanol Plus; Ibu-Buscapina; Ibu-Tetralgin; Ibudolofrix; Ibudristan; Ibumar Migra; Ibunastizol; Ibupirac Fem; Ibupirac Flex; Ibupirac Migra; Mensalgin; Migral II; Novo Wilpan; Roveril; Supragesic;
Australia: Dimetapp Headcold & Flu; Nurofen Cold & Flu; Nurofen Plus; Panafen Plus; Sudafed Sinus & Anti-inflammatory Pain Relief; Tri-Profen Cold & Flu;
Austria: Advil Cold; Ardinex;
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Belgium: Adulfen Codeine;
Brazil: Algi-Itamanil; Algi-Reumatril; Algifen; Fymnal; Reuplex;
Canada: Advil Cold & Sinus; Advil Cold & Sinus Plus; Childrens Advil Cold; Dristan Sinus; Robax Platinum; Sudafed Sinus Advance; Vicks DayQuil Sinus & Pain Relief;
The pharmaceutical companies our pharmacies buy from follow strict WHO standards for GMP.
Chile: Adona; Artritapsin; Butartrol; Deucodol Plus; Dioran; Dolnix; Dolo Winasorb; Dolo-Niofen; Dolo-Octirona; Dolonase; Gedol; Ibupirac Compuesto; Ibupirac Flu; Ipson-D; Midol; Neo Butartrol; Niofen Flu; Predual DI; Silartrin; Termo-Niofen;
Czech Republic: Advil Cold; Ardinex; Ibu-Hepa; Ibufein; Modafen;
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Finland: Ardinex; Burana-C;
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France: Anadvil Rhume; Cliptol; Nurofen Rhume; Rhinadvil; Rhinathiol Rhume; Rhinureflex; Vicks Rhume;
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Greece: Nurofen CF; Vicks;
Hungary: Advil Cold; Algoflex-M; Deep Relief; Nurofen Cold & Flu; Rhinathiol Cold;
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India: Acks; Anaflam; Answell; Bruace; Cipgesic Plus; Combiflam; Duoflam; Duoflam Plus; Emflam Plus; Flexon; Flexon-MR; Ibu-Proxyvon; Ibuflamar-P; Ibugesic Plus; Ibugesic-M; Reactine Forte; Reducin- A; Robiflam; Somaflam;
Indonesia: Aknil; Axalan; Iremax; Limasip; Neo Rheumacyl; Neuralgin; Shelrod-Plus;
Ireland: Advil Cold & Flu; Codafen Continus; Nurofen Cold & Flu; Nurofen Plus; Israel: Nurofen Cold & Flu;
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Italy: Solviflu; Vicks Flu-Action;
Japan: Colgen Kowa IB Toumei;
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Mexico: Algitrin; Bipasmin Compuesto NF; Carbager-Plus; Dualgos; Sinutab Advance;
New Zealand: Nurofen Cold & Flu; Nurofen Plus;
Philippines: Alaxan; Anoflam; Brustan; Flexigesic; Muskelax; Restolax; Selxan;
Poland: Ardinex; Dip Rilif; Ibalgin Sport; Ibuprom Zatoki; Metafen; Modafen; Nurofen Antigrip; Nurofen Plus;
Russia: Brustan (Брустан); Ibuclin (Ибуклин); Novigan (Новиган); Nurofen Plus (Нурофен Плюс);
South Africa:
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France: Advil CS; Dentopain; Gen-Payne; Ibucod; Ibumol; Ibupain; Ibupain Forte; Lotem; Mybucod; Mybulen; Mypaid; Myprodol; Nurofen Cold & Flu; Sinumax IB;
Spain: Nurofen Complex; Salvarina;
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Sweden: Ardinex;
Switzerland: Ibufen-L;
Thailand: Alaxan PI; Brustan; Cetan; Dologen; Kintal; Rumatifen-Plus; Skelan;
Turkey: Nurofen Cold & Flu; UAE: Profinal Cold & Sinus; Profinal FM; Profinal XP;
UK or Britain: Codafen Continus; Cuprofen Plus; Deep Relief; Lemsip Flu 12Hr; Lemsip Pharmacy Powercaps; Non- Drowsy Sudafed Dual Relief Max; Nurofen Cold & Flu; Nurofen Plus; Nurofen Sinus; Orbifen Cold & Flu; Solpadeine Migraine; Solpaflex;
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US or USA: Advil Allergy Sinus; Advil Cold & Sinus; Advil PM; Anadar Cold & Flu; Childrens Advil Cold; Childrens Ibuprofen Cold; Childrens Motrin Cold; Combunox; Dimetapp Childrens Cold & Fever; Dimetapp Sinus; Dristan Sinus; Ibudone; Motrin IB Sinus; Reprexain; Sine-Aid IB; Vicoprofen;
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Venezuela: Brudol; Brugesina; Colfene; Femmexultra; Ibucoden.
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