Glucotrol XL (Glipizide)
Class and Category of Drug
Before you buy Glucotrol XL (Glipizide) online, read common information about the medication.
Chemical class: Sulfonylurea
Therapeutic class: Antidiabetic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Glucotrol XL (Glipizide) online , you must read how it works.
To control blood glucose level in type 2 diabetes mellitus
E.R. Tablets,/h3>
Adults. Initial: 5 mg daily with breakfast.
Dosage increased by 5 mg daily every 3 mo, if needed. Maintenance: 5 to 10 mg daily. Maximum: 20 mg daily.
Tablets
Adults. Initial: 5 mg 30 min before first meal of day. Dosage adjusted by 2.5 to 5 mg every 2 to 3 days. For daily dose of 15 mg or less, give as a single dose. For dose above 15 mg daily, give in 2 divided doses. Maximum: 40 mg daily.
As adjunct to or replacement for insulin therapy in type 2 diabetes mellitus
Capsules,Tablets
Adults who need more than 20 units insulin daily. 5 mg daily, while decreasing insulin dosage by one-half. Further insulin reductions are based on clinical response.
Dosage Adjustment Initial dosage reduced to 2.5 mg daily if needed for patients over age 65 and those with hepatic disease.
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Contraindications of Drug
Read contraindications if you want cheap Glucotrol XL (Glipizide) online.
Diabetes complicated by pregnancy; diabetic coma; hypersensitivity to glipizide, sulfonylureas, or their components; ketoacidosis; sole therapy for type 1 diabetes mellitus
Generic Drug Interactions
Drugs
ACE inhibitors, anabolic steroids, androgens, azole antifungals, bromocriptine, chloramphenicol, disopyramide, fibric acid derivatives, guanethidine, H2-receptor antagonists, insulin, magnesium salts, MAO inhibitors, methyldopa, octreotide, oral anticoagulants, oxyphenbutazone, phenylbutazone, probenecid, quinidine, salicylates, sulfonamides, tetracycline, theophylline, tricyclic antidepressants, urinary acidifiers: Increased risk of hypoglycemia
asparaginase, calcium channel blockers, cholestyramine, clonidine, corticosteroids,danazol, diazoxide, estrogen, glucagon,hydantoins, isoniazid, lithium, morphine,nicotinic acid, oral contraceptives, phenothiazines, rifabutin, rifampin, sympathomimetics, thiazide diuretics, thyroid drugs, urinary alkalinizers: Increased risk of hyperglycemia
beta blockers: Possibly hyperglycemia or masking of hypoglycemia signs
digitalis glycosides: Increased risk of digitalis toxicity
pentamidine: Initially hypoglycemia and then hyperglycemia if beta cell damage occurs
Foods
all foods: Possibly delayed absorption of tablets if taken within 30 minutes of meal
Activities
alcohol use: Altered blood glucose control (usually hypoglycemia)
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, anxiety, asthenia, chills, depression, dizziness, fatigue, headache, hypertonia, hypoesthesia, insomnia, malaise, migraine headache, nervousness, paresthesia, somnolence, syncope, tremor, vertigo
Cardiovascular: Arrhythmias, edema, hypertension, vasculitis
Eyes, Ears, Nose, And Throat: Blurred vision, conjunctivitis, eye pain, pharyngitis, retinal hemorrhage, rhinitis, taste perversion, tinnitus
Endocrine: Hypoglycemia
Gastrointestinal: Abdominal pain, anorexia, constipation, diarrhea, elevated liver function test results, epigastric discomfort or fullness, flatulence, heartburn, hunger, nausea, proctocolitis, trace blood in stool, vomiting
Genitourinary: Darkened urine, decreased libido, dysuria, polyuria
Hematologic: Agranulocytosis, aplastic anemia, eosinophilia, hemolytic anemia, hepatic porphyria, leukopenia, pancytopenia
Musculoskeletal: Arthralgia, leg cramps, myalgia
Respiratory: Dyspnea
Skin: Allergic skin reactions, diaphoresis, eczema, erythema multiforme, exfoliative dermatitis, flushing, jaundice, lichenoid reactions, maculopapular or morbilliform rash, photosensitivity, urticaria
Other: Disulfiram-like reaction
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Nursing Considerations for Generic Drugs
• Use cautiously in patients with glucose 6-phosphate dehydrogenase deficiency because hemolytic anemia may develop. Monitor patient's CBC closely.
• To improve blood glucose control, give drug in divided doses instead of once daily.
• Check blood glucose level at least three times daily for a patient switching from insulin to glipizide. Patients who take more than 40 units of insulin daily may need hospitalization during transition.
• If patient gradually loses responsiveness to glipizide, expect to give a second antidiabetic to maintain blood glucose control.
• Monitor fasting blood glucose level to determine response to drug. Expect to check glycosylated hemoglobin every 3 to 6 months or as ordered to evaluate long-term blood glucose control.
• Expect to switch patient to insulin therapy, as prescribed, during physical stress, such as infection, surgery, or trauma.
WARNING Risk of hypoglycemia is higher when giving glipizide to a malnourished or debilitated patient or one with renal, hepatic, pituitary, or adrenal insufficiency.
Do I need a prescription to buy generic Glucotrol XL (Glipizide) in your online drug store?
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