carisoprodol
Soma, Vanadom
Class and Category of Drug
Chemical class: Dicarbamate
Therapeutic class: Skeletal muscle relaxant
Pregnancy category: C
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Drug Indications and Dosages
As adjunct to relieve acute musculoskeletal pain and stiffness
Tablets (Soma)
Adults and children over age 16.250 to 350 mg t.i.d. and at bedtime.
Tablets (Vanadom)
Children ages 5 to 12. 6.25 mg/kg t.i.d. and at bedtime.
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Contraindications of Drug
Hypersensitivity or idiosyncratic reactions to carisoprodol, to its components, or to meprobamate-related compounds; intermittent porphyria
Generic Drug Interactions
Drugs
CNS depressants, psychotropic drugs:Additive CNS depression
fluvoxamine, omeprazole: Increased blood carisoprodol level
rifampin, St. John's wort: Decreased blood carisoprodol level
Activities
alcohol use: Additive CNS depression
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Drugs Adverse Reactions
Central Nervous System: Agitation, ataxia, depression, dizziness, drowsiness, fever, headache, insomnia, irritability, seizures, somnolence, syncope, tremor, vertigo
Cardiovascular: Orthostatic hypotension, tachycardia
Eyes, Ears, Nose, And Throat: Diplopia, transient vision loss
Gastrointestinal: Epigastric discomfort, hiccups, nausea, vomiting
Hematologic: Eosinophilia
Skin: Erythema multiforme, facial flushing, pruritus, rash
Other: Drug dependence or withdrawal
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Nursing Considerations for Generic Drugs
• Use carisoprodol cautiously in patients with history of drug addiction and in patients taking other CNS depressants, including alcohol.
• Carisoprodol therapy should last no longer than 3 weeks.
• Monitor patient closely for hypersensitivity or idiosyncratic reactions. They typically occur before the fourth dose in patients who have no previous carisoprodol exposure.
• Provide rest and other pain-relief measures.
• To avoid mild withdrawal symptoms, expect to taper therapy as prescribed, rather than stopping it abruptly.
Carisoprodol
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
The United States Pharmacopeia 31, 2008: Carisoprodol and Aspirin Tablets; Carisoprodol Tablets; Carisoprodol, Aspirin, and Codeine Phosphate Tablets.
Proprietary Preparations
Argentina: Listaflex;
Canada: Soma;
Denmark: Somadril;
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India: Carisoma;
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Mexico: Somacid;
Norway: Somadril;
Spain: Mio Relax;
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Sweden: Somadril;
Thailand: Myolax;
UK or Britain: Carisoma;
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US or USA: Soma.
Multi-ingredient
Argentina: Algiseda; Flexicamin; Flexicamin A; Flexicamin B12; Flogiatrin; Flogiatrin B12; Ketazon Flex; Mefenix Relax; Naprontag Flex; Rumisedan Fuerte; Solocalm Plus; Solocalm-Flex;
Brazil: Algi-Butazolon; Algi-Tanderil; Beserol; Cedrilax; Diclofetamol; Dorilax; Flexalgin; Mio-Citalgan; Mioflex; Mioflex A; Mionevrix; Paceflex; Sanilax; Sedilax; Tandene; Tanderalgin; Tandriflan; Tandrilax; Torsilax; Trilax;
Czech Republic: Scutamil C;
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Finland: Somadril Comp;
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Greece: Relacton-C;
Hungary: Scutamil C;
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India: Carisoma Compound; Somaflam;
Indonesia: New Skelan; Somadril Compound;
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Italy: Soma Complex;
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Mexico: Blocacid; Contraxen; Dolaren; Dorsal; Duoflex; Empatil; Naxodol; Profenlax; Somalgesic;
Spain: Flexagil; Relaxibys;
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Sweden: Somadril Comp;
Thailand: Alaxan; Asialax; Cariso-Co; Carisoma Compound; Caritasone; Cenpadol; Muscelax; Myophen; Polixan;
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US or USA: Sodol Compound; Soma Compound with Codeine; Soma Compound;
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Venezuela: Cotar; Flexidone; Praxona.
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