Lamictal DC (Lamotrigine) - General Health
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Top » Catalog » General Health » Lamictal DC (Lamotrigine)


Lamictal DC (Lamotrigine)

$189.89


Buy generic Lamictal DC (Lamotrigine) online without prescription

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Lamictal DC (Lamotrigine)

Class and Category of Drug

Before you buy Lamictal DC (Lamotrigine) online, read common information about the medication.

Chemical class: Phenyltriazine

Therapeutic class: Anticonvulsant

Pregnancy category: C

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Drug Indications and Dosages

Before purchase Lamictal DC (Lamotrigine) online , you must read how it works.

As adjunct to treat partial seizures; to treat generalized seizures of Lennox-Gastaut syndrome; to treat primary generalized tonic-clonic seizures

ChewableTablets,Tablets

Adults and adolescents age 16 and over converting from valproate. 25 mg every other day for 2 wk followed by 25 mg once daily for 2 wk. Then increased by 25 to 50 mg daily every 1 to 2 wk until dosage of 200 mg daily is achieved. At this time valproate dosage decreased to 500 mg daily by decrements no greater than 500 mg daily every wk and then maintained at 500 mg daily for 1 wk. After completion of week, lamotrigine dosage increased to 300 mg daily and maintained for 1 wk while valproate dosage decreased to 250 mg daily and maintained for 1 wk. Then lamotrigine dosage increased by 100 mg daily every wk to achieve maintenance dose of 500 mg daily. Once achieved, valproate therapy is discontinued.

As maintenance therapy for bipolar 1 disorder to delay occurrence of mood episodes (depression, mania, hypomania, mixed episodes)

Chewable Tablets, Tablets

Adults not taking carbamazepine, phenytoin, phenobarbital, primidone, rifampin, or valproate. 25 mg once daily for 2 wk, followed by 50 mg once daily for 2 wk, followed by 100 mg once daily for 1 wk and then increased to 200 mg once daily as maintenance dose. Maximum: 200 mg daily.

Adults taking valproate. 25 mg every other day for 2 wk, followed by 25 mg once daily for 2 wk, followed by 50 mg once daily for 1 wk, and then increased to 100 mg once daily as maintenance dose.

Adults taking carbamazepine, phenytoin, phenobarbital, primidone, or rifampin, but not valproate. 50 mg once daily for 2 wk followed by 100 mg once daily in divided doses for 2 wk, followed by 200 mg once daily in divided doses for 1 wk and then increased to 300 mg daily in divided doses for 1 wk and then increased to 400 mg daily in divided doses as maintenance dose.

Dosage Adjustment

For patient starting or stopping estrogen-containing oral contraceptives, lamotrigine dosage may need to be adjusted on individual basis. For patient with moderate to severe liver impairment without ascites, dosage reduced by 25%. For patient with severe liver impairment with ascites, dosage reduced by 50%.

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Generic Drug Interactions

Drugs

acetaminophen (long-term use): Possibly decreased blood lamotrigine level carbamazepine: Decreased blood lamotrigine level; possibly increased risk of dizziness, diplopia, ataxia, and blurred vision folate inhibitors, such as co-trimoxazole and methotrexate: Increased blood lamotrigine level

oral contraceptives: Decreased blood lamotrigine level during 3 weeks of active hormonal therapy and increased blood lamotrigine level during 1 week of inactive hormonal therapy; possibly reduced effectiveness of oral contraceptives oxcarbazepine: Possibly increased risk of headache, dizziness, nausea, and somnolence

phenobarbital, phenytoin, primidone: Decreased blood lamotrigine level, possibly increased CNS depression topiramate: Increased topiramate level valproic acid: Increased lamotrigine level, decreased lamotrigine clearance, decreased blood valproic acid level

Activities

alcohol use: Possibly increased CNS depression

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Drugs Adverse Reactions

Central Nervous System: Amnesia, anxiety, ataxia, confusion, depression, dizziness, drowsiness, emotional lability, fever, headache, increased seizure activity, lack of coordination, suicidal ideation

Cardiovascular: Chest pain

Eyes, Ears, Nose, And Throat: Blurred vision, diplopia, dry mouth, nystagmus

Gastrointestinal: Abdominal pain, anorexia, constipation, diarrhea, hepatic failure, vomiting

Hematologic: Anemia, aplastic anemia, disseminated intravascular coagulation, eosinophilia, leukopenia, neutropenia, pancytopenia, pure red cell aplasia, thrombocytopenia

Skin: Petechiae, photosensitivity, pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis

Other: Acute multiorgan failure, angioedema, flulike symptoms, lymphadenopathy

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Lamotrigine

Preparations

International Brand Drug Names

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Proprietary Preparations


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