Lasuna (Levofloxacin)
Class and Category of Drug
Before you buy Lasuna (Levofloxacin) online, read common information about the medication.
Chemical class: Fluoroquinolone
Therapeutic class: Antibiotic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Lasuna (Levofloxacin) online , you must read how it works.
To reduce incidence or progression of inhalation anthrax after exposure to aerosolized Bacillus anthracis
Tablets, Intravenous Infusion, Oral Solution
Adults and children weighing more than 50 kg (110 lb). 500 mg (over 60 min for intravenous infusion) daily for 60 days.
Children weighing less than 50 kg. 8 mg/kg (over 60 min for intravenous infusion) every 12 hr for 60 days. Maximum: 250 mg/dose.
To treat acute maxillary sinusitis caused by Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae
Tablets, Intravenous Infusion, Oral Solution
Adults. 500 mg daily (over 60 to 90 min for intravenous infusion) for 10 to 14 days. Or 759 mg daily for 5 days.
To treat acute exacerbation of chronic bacterial bronchitis caused by H. influenzae, H. parainfluenzae, M. catarrhalis, S. pneumoniae, or Staphylococcus aureus
Tablets, Intravenous Infusion, Oral Solution
Adults. 500 mg daily (over 60 to 90 min for intravenous infusion) for 7 days.
To treat community-acquired pneumonia caused by Chlamydia pneumoniae, H. influenzae, H. parainfluenzae, Klebsiella pneumoniae, Legionella pneumophila, M. catarrhalis, Mycoplasma pneumoniae, S. aureus, or S. pneumoniae
Tablets, Intravenous Infusion, Oral Solution
Adults. 500 mg daily (over 60 to 90 min for intravenous infusion) for 7 to 14 days. Alternatively, for infection caused by C. pneumoniae, H. influenzae, H. parainfluenzae, M. pneumoniae, or S. pneumoniae, 750 mg daily (over 60 to 90 min for intravenous infusion) for 5 days.
To treat uncomplicated Urinary tract infection caused by Escherichia coli, K. pneumoniae, or Staphylococcus saprophyticus
Tablets, Intravenous Infusion, Oral Solution
Adults. 250 mg daily (over 60 to 90 min for intravenous infusion) for 3 days.
To treat complicated Urinary tract infection caused by Enterococcus faecalis, E. cloacae, E. coli, K. pneumoniae, Proteus mirabilis, or Pseudomonas aeruginosa or acute pyelonephritis caused by E. coli
Tablets, Intravenous Infusion, Oral Solution
Adults. 250 mg daily (over 60 to 90 min for intravenous infusion) for 10 days.
To treat complicated Urinary tract infection caused by E. coli, K. pneumoniae, or P. mirabilis or acute pyelonephritis caused by E. coli
Tablets, Intravenous Infusion, Oral Solution
Adults. 750 mg daily (over 90 min for intravenous infusion) for 5 days.
To treat mild to moderate skin and soft-tissue infections caused by S. aureus or Streptococcus pyogenes
Tablets, Intravenous Infusion, Oral Solution
Adults. 500 mg daily (over 60 to 90 min for intravenous infusion) for 7 to 10 days.
To treat complicated skin and soft-tissue infections caused by methicillin-sensitive Enterococcus faecalis, Proteus mirabilis, S. aureus, or S. pyogenes; to treat nosocomial pneumonia caused by S. aureus, Pseudomonas aeruginosa, Serratia marcescens, E. coli, K. pneumoniae, H. influenzae, or S. pneumoniae
Tablets, Intravenous Infusion, Oral Solution
Adults. 750 mg daily (over 60 to 90 min for intravenous infusion) for 7 to 14 days.
To treat chronic bacterial prostatitis caused by E. coli, E. faecalis, or S. epidermidis
Tablets, Intravenous Infusion, Oral Solution
Adults. 500 mg daily (over 60 to 90 min for intravenous infusion) for 28 days.
Dosage Adjustment For complicated Urinary tract infection in patients with creatinine clearance of 10 to 19 ml/min/1.73 m2, 250 mg initially and then maintenance dosage of 250 mg every 48 hr. For complicated skin and soft-tissue infections and nosocomial pneumonia when creatinine clearance is 19 ml/ min/1.73 m2 or less, 750 mg initially and then maintenance dosage of 500 mg every 48 hr; when creatinine clearance is 20 to 49 ml/min/1.73 m2, 750 mg initially and then maintenance dosage of 750 mg every 48 hr. For all other indications, when creatinine clearance is 19 ml/min/1.73 m2 or less, 500 mg initially and then maintenance of 250 mg every 48 hr; when creatinine clearance is 20 to 49 ml/min/1.73 m2, 500 mg initially and then maintenance dosage of 250 mg every 24 hr.
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Contraindications of Drug
Read contraindications if you want cheap Lasuna (Levofloxacin) online.
Hypersensitivity to levofloxacin, other fluoroquinolones, or their components
Generic Drug Interactions
Drugs
aluminum-, calcium-, or magnesium-containing antacids; didanosine; iron; sucralfate; zinc: Reduced gastrointestinal absorption of levofloxacin
antineoplastics: Decreased blood levofloxacin level
cimetidine: Increased blood levofloxacin level
cyclosporine: Increased risk of nephrotoxicity NSAIDs: Possibly increased CNS stimulation and risk of seizures
oral anticoagulants: Increased anticoagulant effect and risk of bleeding
oral antidiabetic drugs: Possibly hyperglycemia or hypoglycemia
theophylline: Increased blood theophylline level and risk of toxicity
Activities
sun exposure: Increased risk of photosensitivity
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Drugs Adverse Reactions
Central Nervous System: Anxiety, CNS stimulation, dizziness, fever, headache, increased ICP, insomnia, light-headedness, nervousness, paranoia, peripheral neuropathy, psychosis, seizures, sleep disturbance, suicidal ideation
Cardiovascular: Arrhythmias, leukocytoclastic vasculitis, prolonged QT interval, torsades de pointes, vasculitis, vasodilation
Eyes, Ears, Nose, And Throat: Blurred vision, decreased visual acuity, diplopia, dysphonia, scotoma, taste perversion, tinnitus
Endocrine: Hyperglycemia, hypoglycemia
Gastrointestinal: Abdominal pain, acute hepatic necrosis or failure, anorexia, constipation, diarrhea, flatulence, hepatitis, hepatotoxicity, indigestion, jaundice, nausea, pseudomembranous colitis, vomiting
Genitourinary: Acute renal failure or insufficiency, crystalluria, interstitial nephritis, vaginal candidiasis
Hematologic: Agranulocytosis, aplastic anemia, eosinophilia, hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia
Musculoskeletal: Arthralgia, back pain, myalgia, rhabdomyolysis, tendon or muscle rupture
Respiratory: Allergic pneumonitis
Skin: Photosensitivity, pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Other: Anaphylaxis, angioedema, multi-organ failure, serum sickness
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Nursing Considerations for Generic Drugs
• Use levofloxacin cautiously in patients with renal insufficiency. Monitor renal function as appropriate during treatment.
• Use drug cautiously in patients with CNS disorders, such as epilepsy, that may lower the seizure threshold. Also use cautiously in patients taking corticosteroids, especially elderly patients, because of increased risk of tendon rupture.
• Expect to obtain culture and sensitivity tests before levofloxacin treatment begins.
• Avoid giving drug within 2 hours of antacids.
• Give parenteral form over 60 to 90 minutes, depending on dosage, because bolus or rapid intravenous delivery may cause hypotension.
WARNING Stop levofloxacin at first sign of hypersensitivity, including rash and jaundice, because drug may lead to anaphylaxis. Reaction may occur after first dose. Expect to give epinephrine and provide supportive care.
• Monitor blood glucose level, especially in diabetic patient who takes an oral antidiabetic or uses insulin, because levofloxacin may alter blood glucose level. If so, notify prescriber, stop drug immediately if patient has hypoglycemia, and provide prescribed treatment.
• Monitor QT interval if needed. If it lengthens, notify prescriber at once and stop drug. Patients with hypokalemia, significant bradycardia, or cardiomyopathy and those receiving a class IA or III antiarrhythmic shouldn't receive levofloxacin.
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