Lisinopril (Zestril)
Class and Category of Drug
Before you buy Lisinopril (Zestril) online, read common information about the medication.
Chemical class: Lysine ester of enalaprilat
Therapeutic class: Antihypertensive, vasodilator
Pregnancy category: C (first trimester), D (later trimesters)
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Drug Indications and Dosages
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To manage uncomplicated essential hypertension
Tablets
Adults. Initial: 10 mg daily. Maintenance: 20 to 40 mg daily. Maximum: 80 mg daily.
Dosage Adjustment For patients with renal failure, initial dosage reduced to 5 mg daily if creatinine clearance is 10 to 30 ml/ min/1.73 m2 and to 2.5 mg daily if creatinine clearance is less than 10 ml/min/ 1.73 m2. For patients receiving a diuretic, initial dosage reduced to 5 mg daily. Children age 6 and over with a GFR of at least 30 nil/min/1.73 m2. Initial: 0.07 mg/ kg daily, adjusted according to blood pressure response up to 5 mg daily. Maximum: 0.61 mg/kg or 40 mg daily.
To treat heart failure, along with digoxin and diuretics
Tablets
Adults. Initial: 5 mg daily. Maintenance: 5 to 20 mg daily. Maximum: 80 mg daily.
Dosage Adjustment For patients with hyponatremia or creatinine clearance of 30 ml/min/1.73 m2 or less, initial dosage reduced to 2.5 mg daily.
To improve survival in hemodynamically stable patient after acute Ml
Tablets
Adults. 5 mg within 24 hr after onset of symptoms, followed by 5 mg after 24 hr and 10 mg after 48 hr. Maintenance: 10 mg daily for 6 wk. Maximum: 80 mg daily.
Dosage Adjustment For patients with baseline systolic blood pressure of 120 mm
Hg or less, initial dosage decreased to 2.5 mg daily for first 3 days after MI. If systolic blood pressure falls to 100 mm Hg or less during therapy, maintenance dosage decreased to 2.5 to 5 mg as tolerated; if systolic blood pressure is 90 mm Hg or less for more than 1 hr, drug is discontinued.
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Generic Drug Interactions
Read contraindications if you want cheap Lisinopril (Zestril) online.
Drugs
allopurinol, bone marrow depressants (such as methotrexate), procainamide, systemic corticosteroids: Increased risk of potentially fatal neutropenia or agranulocytosis
cyclosporine, potassium-sparing diuretics, potassium supplements: Increased risk of hyperkalemia
diuretics, other antihypertensives: Increased hypotensive effect
insulin, oral antidiabetics: Increased risk of hypoglycemia
lithium: Increased blood lithium level and risk of lithium toxicity
NSAIDs: Possibly reduced antihypertensive effect, reduced renal function in patients with preexisting renal dysfunction
sympathomimetics: Possibly reduced antihypertensive effect
Foods
high-potassium diet, potassium-containing salt substitutes: Increased risk of hyperkalemia
Activities
alcohol use: Possibly increased hypotensive effect
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Drugs Adverse Reactions
Central Nervous System: Ataxia, confusion, depression, dizziness, fatigue, headache, mood alterations, nervousness, stroke, syncope, transient ischemic attack, vertigo
Cardiovascular: Arrhythmias, chest pain, hypotension, MI, orthostatic hypotension, palpitations, peripheral edema, vasculitis
Endocrine: Hyperglycemia, syndrome of inappropriate ADH secretion
Eyes, Ears, Nose, And Throat: Olfactory disturbance
Gastrointestinal: Abdominal pain, anorexia, cholestatic jaundice, diarrhea, elevated liver enzyme levels, fulminant hepatic necrosis, gastritis, hepatitis, indigestion, nausea, pancreatitis, vomiting
Genitourinary: Acute renal failure, decreased libido, impotence, pyelonephritis
Hematologic: Agranulocytosis, anemia, hemolytic anemia, neutropenia, thrombocytopenia
Musculoskeletal: Muscle spasms, myalgia
Respiratory: Bronchospasm, cough, dyspnea, paroxysmal nocturnal dyspnea, pulmonary embolism and infarction, upper respiratory tract infection
Skin: Alopecia, cutaneous pseudolymphoma, diaphoresis, erythema, flushing, herpes zoster, infections, pemphigus, photosensitivity, pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Other: Anaphylaxis, angioedema
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Nursing Considerations for Generic Drugs
• Use lisinopril cautiously in patients with fluid volume deficit, heart failure, impaired renal function, or sodium depletion.
• To prepare pediatric suspension, add 10 ml purified water to a polyethylene terephthalate (PET) bottle containing ten 20-mg tablets and shake for at least 1 minute. Add 30 ml of Bicitra diluent and 160 ml of Ora-Sweet SF to concentrate in PET bottle and shake gently for several seconds. Refrigerate up to 4 weeks. Shake suspension before each use.
• Monitor blood pressure often, especially early in treatment. If excessive hypotension develops, expect to withhold drug for several days.
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Lisinopril
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
British Pharmacopoeia, 2008 edition: Lisinopril Tablets;
The United States Pharmacopeia 31, 2008: Lisinopril Tablets.
Proprietary Preparations
Argentina: Doxapril; Lisinal; Sedotensil; Tensopril; Tersif; Zestril;
Australia: Fibsol; Liprace; Lisinobell; Lisodur; Prinivil; Zestril;
Austria: Acemin; Acetan; Lisihexal; Lisinostad; Lisinotyrol; Prinivil;
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Belgium: Novatec; Zestril;
Brazil: Lisopril; Listril; Lonipril; Prilcor; Prinivil; Prinopril; Vasojet; Zestril; Zinopril;
Canada: Prinivil; Zestril;
The pharmaceutical companies our pharmacies buy from follow strict WHO standards for GMP.
Chile: Acerdil; Lipreren; Presokin; Tonotensil; Zestril;
Czech Republic: Dapril; Diroton; Irumed; Lipribela; Lisigamma; Lisipril; Listril; Prinivil;
Denmark: Acepril; Lanatin; Lisinogen; Vivatec; Zestril;
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Finland: Lisipril; Vivatec; Zestril;
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France: Prinivil; Zestril;
Germany: Acerbon; Coric; Lisi; Lisi Lich; Lisi-Puren; Lisibeta; Lisidoc; Lisigamma; Lisihexal; Lisodura;
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Greece: Adicanil; Axelvin; Gnostoval; Hyperliz; Icoran; Landolaxin; Leruze; Lisinospes; Lisodinol; Mealis; Nafordyl; Perenal; Press-12; Pressuril; Prinivil; Terolinal; Thriusedon; Tivirlon; Vercol; Veroxil; Z-Bec; Zestril;
Hong Kong: Acepril; Cipril; Prinivil; Zestril;
Hungary: Conpres; Lisdene; Lisopress; Press-12;
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India: Biopril; Cipril; Linoril; Linvas; Lipril; Lisoril; Normopril;
Indonesia: Interpril; Linoxal; Noperten; Nopril; Odace; Zestril;
Ireland: ByZestra; Carace; Lisopress; Lispril; Zesger; Zestan; Zestril; Israel: Tensopril;
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Italy: Alapril; Prinivil; Zestril;
Japan: Longes;
Malaysia: Acepril; Dapril; Prinivil; Ranopril; Zestril;
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Mexico: Alfaken; Dosteril; Linospril; Priniser; Prinivil; Zestril;
Netherlands or Holland: Novatec; Zestril;
Norway: Vivatec; Zestril;
New Zealand: Prinivil; Zestril;
Philippines: Sinolip; Zestril;
Poland: Diroton; Lisdene; Lisihexal; Lisinoratio; Lisiprol; Prinivil;
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Portugal: Benzin; Ecapril; Farpresse; Lipril; Lisinol; Lisopress; Prinivil; Zestril;
Russia: Dapril (Даприл); Diroton (Диротон); Irumed (Ирумед); Lisinoton (Лизинотон); Lisoril (Лизорил); Listril (Листрил); Liten (Литэн); Sinopril (Синоприл);
South Africa:
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France: Prilosin; Prinivil; Renotens; Sinopren; Zemax; Zeprosil; Zestril; Zetomax;
Singapore: Dapril; Lisdene; Lisoril; Prinivil; Zestril;
Spain: Doneka; Iricil; Likenil; Prinivil; Secubar; Tensikey; Zestril;
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Sweden: Vivatec; Zestril;
Switzerland: Corprilin; Lisitril; Lisopril; Prinil; Tobicor; Zestril;
Thailand: Lisdene; Lispril; Zestril;
Turkey: Acerilin; Rilace; Sinopryl; Zestril; UAE: Lisotec;
UK or Britain: Carace; Zestril;
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US or USA: Prinivil; Zestril;
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Venezuela: Cotensil; Lisilet; Prinivil; Rantex; Tonoten.
Multi-ingredient
Argentina: Tensopril D; Zestoretic;
Austria: Acecomb; Acelisino comp; Co-Acetan; Co-Hypomed; Co-Lisinostad; Lisihexal comb; Lisinocomp; Lisinopril comp; Zestoretic;
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Belgium: Co-Lisinopril; Merck-Co- Lisinopril; Novazyd; Zestoretic;
Brazil: Lisinoretic; Lisoclor; Lisonotec; Lonipril-H; Prinzide; Zestoretic;
Canada: Prinzide; Zestoretic;
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Chile: Acerdil- D; Tonotensil D; Zestoretic;
Czech Republic: Lipribela plus H;
Denmark: Lisinoplus; Vivazid; Zestoretic;
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Finland: Acercomp; Lisipril Comp; Vivatec Comp;
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France: Prinzide; Zestoretic;
Germany: Acercomp; Coric Plus; Lisi-Puren comp; Lisibeta comp; Lisigamma HCT; LisiLich comp; Lisinopril comp; Lisinopril HCT; Lisiplus; Lisodura plus;
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Greece: Prinzide; Z-Bec Plus; Zestoretic;
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India: Amlopres L; Amlosafe-LS; Biopril- AM; Calchek L; Cipril-H; Lisoril-5HT;
Indonesia: Zestoretic;
Ireland: Carace Plus; Lispril-hydrochlorothiazide; Zesger Plus; Zestoretic;
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Italy: Nalapres; Prinzide; Zestoretic;
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Mexico: Prinzide; Zestoretic;
Netherlands or Holland: Lisidigal HCT; Novazyd; Zestoretic;
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Portugal: Ecamais; Lisoplus; Prinzide; Tiazinol; Zestoretic;
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South Africa:
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France: Lisoretic; Zestoretic; Zetomax Co;
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Sweden: Zestoretic;
Switzerland: Co-Lisinopril; Corpriretic; Lisitril comp; Lisopril plus; Prinzide; Tobicor Plus; Zestoretic;
Turkey: Rilace Plus; Sinoretik; Zestoretic;
UK or Britain: Carace Plus; Caralpha; Lisicostad; Zestoretic;
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US or USA: Prinzide; Zestoretic;
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Venezuela: Lisiletic.
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