Lotensin (Benazepril) - Blood Pressure/Cholesterol
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Top » Catalog » Blood Pressure/Cholesterol » Lotensin (Benazepril)


Lotensin (Benazepril)

$49.80


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Lotensin (Benazepril)

Class and Category of Drug

Before you buy Lotensin (Benazepril) online, read common information about the medication.

Chemical class: Ethylester of benazeprilat

Therapeutic class: Antihypertensive

Pregnancy category: D

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Drug Indications and Dosages

Before purchase Lotensin (Benazepril) online , you must read how it works.

To control hypertension alone or with a thiazide diuretic

Tablets

Adults who don't receive a diuretic. Initial: 10 mg daily. Maintenance: 20 to 40 mg daily as a single dose or in two divided doses.

Adults who receive a diuretic. 5 mg daily.

Dosage Adjustment Initial dosage of 5 mg/day for patients with impaired renal function and creatinine clearance less than 30 ml/min/1.73 m2; then increased gradually until blood pressure is controlled or dosage reaches maximum of 40 mg daily.

Tablets, Suspension

Children age 6 and over with glomerular filtration rate of 30 ml/min/1.73 m2 or higher. Initial: 0.2 mg/kg daily. Maximum: 0.6 mg/kg daily or 40 mg daily.

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Generic Drug Interactions

Drugs

antacids: Possibly decreased bio availability of benazepril; separate doses by 2 hours

antidiabetics (oral): Possibly increased risk of hypoglycemia

capsaicin: Possibly induction or exacerbation of ACE cough caused by benazepril digoxin: Increased serum digoxin level diuretics: Possibly excessive hypotension

indomethacin: Reduced hypotensive effects of benazepril

lithium: Increased serum lithium level and risk of lithium toxicity phenothiazines: Possibly increased therapeutic and adverse effects of benazepril potassium preparations, potassium-sparing diuretics: Possibly increased serum potassium level

sodium aurothiomalate: Increased risk of nitritoid reactions, such as facial flushing, nausea, vomiting, and hypotension

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Drugs Adverse Reactions

Central Nervous System: Anxiety, asthenia, dizziness, drowsiness, fatigue, headache, hypertonia, insomnia, nervousness, paresthesia, sleep disturbance, somnolence, syncope, weakness

Cardiovascular: Angina, electrocardiogram changes, hypotension, orthostatic hypotension, palpitations, peripheral edema

Eyes, Ears, Nose, And Throat: Sinusitis

Endocrine: Hyperglycemia

Gastrointestinal: Abdominal pain, constipation, elevated liver function test results, gastritis, melena, nausea, pancreatitis, small bowel angioedema, vomiting

Genitourinary: Decreased libido, elevated BUN and serum creatinine levels, impotence, nephrotic syndrome, proteinuria, renal insufficiency, urinary tract infection

Hematologic: Agranulocytosis, decreased hemoglobin level, leukopenia, neutropenia, thrombocytopenia

Musculoskeletal: Arthralgia, arthritis, myalgia

Respiratory: ACE cough, asthma, bronchitis, bronchospasm, dyspnea

Skin: Dermatitis, diaphoresis, flushing, photosensitivity, pruritus, rash

Other: Anaphylaxis, angioedema, hyperkalemia, hyponatremia

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Nursing Considerations for Generic Drugs

• Evaluate blood pressure with patient lying down, sitting, and standing before starting benazepril and then every 4 to 8 hours, as appropriate, to monitor effectiveness.

• Monitor urine output and BUN and serum creatinine levels, as needed, before therapy.

WARNING Be alert for angioedema, especially after first dose. If it extends to larynx and patient has laryngeal stridor or signs of airway obstruction, prepare to give epi-nephrine subcutaneously immediately, as prescribed, and discontinue benazepril.

• Monitor WBC count periodically to detect neutropenia and agranulocytosis.

• Check serum potassium and other electrolyte levels to detect electrolyte imbalances.

• To prevent injury caused by orthostatic hypotension, take safety precautions, such as having patient change positions slowly and sit on edge of bed before arising.

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Benazepril

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


The United States Pharmacopeia 31, 2008: Benazepril Hydrochloride Tablets.

Proprietary Preparations


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Multi-ingredient


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