Pravachol (Pravastatin) - Blood Pressure/Cholesterol
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Top » Catalog » Blood Pressure/Cholesterol » Pravachol (Pravastatin)


Pravachol (Pravastatin)

$102.51


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Pravachol (Pravastatin)

Class and Category of Drug

Before you buy Pravachol (Pravastatin) online, read common information about the medication.

Chemical class: Mevinic acid derivative

Therapeutic class: Antihyperlipidemic

Pregnancy category: X

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Drug Indications and Dosages

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To prevent coronary and cardiovascular events in patients at risk, to treat hyperlipidemia

Tablets

Adults. Initial: 10 to 40 mg daily at bedtime, increased every 4 wk, as needed. Maintenance: 10 to 80 mg at bedtime.

Dosage Adjustment For patients with significant renal or hepatic impairment, those taking immunosuppressants, and elderly patients, initial dosage reduced to 10 mg daily at bedtime. For elderly patients and those taking immunosuppressants, maintenance dosage usually limited to 20 mg daily.

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Contraindications of Drug

Read contraindications if you want cheap Pravachol (Pravastatin) online.

Active hepatic disease or unexplained, persistent elevated liver function test results; breastfeeding; hypersensitivity to pravastatin or its components; pregnancy

Generic Drug Interactions

Drugs

cholestyramine, colestipol: Decreased pravastatin bioavailability cyclosporine, erythromycin, gemfibrozil, immunosuppressants, niacin: Increased risk of rhabdomyolysis and acute renal failure oral anticoagulants: Increased bleeding or prolonged PT

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Drugs Adverse Reactions

Central Nervous System: Anxiety, depression, dizziness, fatigue, headache, nervousness, sleep disturbance

Cardiovascular: Angina pectoris, chest pain

Eyes, Ears, Nose, And Throat: Blurred vision, diplopia, rhinitis

Endocrine: Abnormal thyroid function

Gastrointestinal: Abdominal pain, constipation, diarrhea, elevated liver function test results, flatulence, heartburn, indigestion, nausea, pancreatitis, vomiting

Genitourinary: Dysuria, nocturia, urinary frequency

Musculoskeletal: Arthralgia, musculoskeletal cramps or pain, myalgia, myopathy, rhabdomyolysis

Respiratory: Cough, dyspnea, upper respiratory tract infection

Skin: Rash

Other: Angioedema

Nursing Considerations for Generic Drugs

• Use pravastatin cautiously in patients with renal or hepatic impairment and in elderly patients.

• Monitor liver function test results before pravastatin therapy starts, before dosage increases, and periodically throughout therapy, as prescribed.

• Give drug 1 hour before or 4 hours after giving cholestyramine or colestipol.

• Report unexplained muscle aches or weakness and significant increases in CK level to prescriber because drug rarely causes rhabdomyolysis with acute renal failure caused by myoglobinuria. Expect to stop drug and provide supportive care.

• Monitor patient's BUN and serum creatinine levels periodically for abnormal elevations.

• Monitor blood lipoprotein level, as indicated, to evaluate response to therapy.

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Pravastatin

Preparations

International Brand Drug Names

The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.


British Pharmacopoeia, 2008 edition: Pravastatin Tablets;
The United States Pharmacopeia 31, 2008: Pravastatin Sodium Tablets.

Proprietary Preparations


Argentina: Pravacol;
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