Prednisone (Deltasone) - Anti-Allergic/Asthma
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Prednisone (Deltasone)

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Prednisone (Deltasone)

Class and Category of Drug

Before you buy Prednisone (Deltasone) online, read common information about the medication.

Before you buy Prednisone online, read common information about the medication.

Chemical class: Glucocorticoid

Therapeutic class: Anti-inflammatory immunosuppressant

Pregnancy category: Not rated

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Drug Indications and Dosages

Before purchase Prednisone (Deltasone) online , you must read how it works.

Before purchase Prednisone online , you must read how it works.

To treat adrenal insufficiency and acute and chronic inflammatory and immunosuppressive disorders

Oral Solution, Syrup,

Tablets

Adults and adolescents. 5 to 60 mg daily as a single dose or in divided doses. Maximum: 250 mg daily.

To treat adrenogenital syndrome

Oral Solution, Syrup,Tablets

Adults and adolescents. 5 to 10 mg daily.

Children. 5 mg/m2 daily in divided doses b.i.d.

To treat acute exacerbations of multiple sclerosis

Oral Solution, Syrup,Tablets

Adults. 200 mg daily for 1 wk, then 80 mg every other day for 1 mo. Maximum:250 mg daily.

To treat nephrosis in children

Oral Solution, Syrup,Tablets

Children age 10 and over. 20 mg q.i.d.

Children ages 4 to 10.15 mg q.i.d.

Children ages 18 months to 4 years. 7.5 to 10 mg q.i.d.

To treat rheumatic carditis, leukemia, and tumors in children

Oral Solution, Syrup,Tablets

Children. 0.5 mg/kg q.i.d. for 2 to 3 wk; then 0.375 mg/kg q.i.d. for 4 to 6 wk.

As adjunct to treat tuberculosis in children (with concurrent antitubercular therapy)

Oral Solution, Syrup,Tablets

Children. 0.5 mg/kg q.i.d. for 2 mo.

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Contraindications of Drug

Read contraindications if you want cheap Prednisone (Deltasone) online.

Read contraindications if you want cheap Prednisone online.

Hypersensitivity to prednisone or its components, systemic fungal infection

Generic Drug Interactions

Drugs

acetaminophen: Possibly hepatotoxicity (long-term use or high acetaminophen doses)

acetazolamide sodium: Possibly hypernatremia or edema

amphotericin B (parenteral): Possibly severe hypokalemia

anabolic steroids, androgens: Possibly edema and severe acne

antacids: Decreased absorption of prednisone (with long-term use) anticholinergics: Increased intraocular pressure

asparaginase: Increased hyperglycemic effect of asparaginase, possibly neuropathy and disturbances in erythropoiesis carbonic anhydrase inhibitors: Possibly hypocalcemia, hypokalemia, and osteoporosis digoxin: Possibly arrhythmias and digitalis toxicity from hypokalemia diuretics: Possibly decreased natriuretic and diuretic effects of diuretics, severe hypokalemia (with potassium-depleting diuretics)

ephedrine: Increased metabolic clearance of prednisone

estrogens, oral contraceptives: Decreased clearance, increased elimination half-life, and increased therapeutic and toxic effects of prednisone

folic acid: Increased folic acid requirements (with long-term prednisone use) heparin, oral anticoagulants, streptokinase, urokinase: Possibly decreased anticoagulant effect and increased risk of gastrointestinal ulceration and bleeding

immunosuppressants: Increased risk of infection, lymphomas, and other lymphoproliferative disorders isoniazid: Decreased blood isoniazid level mexiletine: Possibly accelerated metabolism and decreased blood level of mexiletine neuromuscular blockers: Increased neuro-muscular blockade

NSAIDs: Increased risk of gastrointestinal ulceration and bleeding, possibly added therapeutic effect when NSAIDs are used to treat arthritis potassium supplements: Decreased effectiveness of both drugs

ritodrine: Increased risk of pulmonary edema in pregnant women salicylates: Possibly decreased blood salicylate level, increased risk of gastrointestinal ulceration and bleeding

sodium-containing drugs: Possibly edema and hypertension

somatrem, somatropin: Inhibited growth response to somatrem or somatropin streptozocin: Increased risk of hyperglycemia toxoids, vaccines: Possibly loss of antibody response, increased risk of neurologic complications

tricyclic antidepressants: Possibly exacerbated adverse psychiatric effects of prednisone troleandomycin: Increased therapeutic and toxic effects of prednisone

Foods

sodium-containing foods: Increased risk of edema and hypertension

Activities

alcohol use: Increased risk of gastrointestinal ulceration and bleeding

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Drugs Adverse Reactions

Central Nervous System: Euphoria, headache, insomnia, nervousness, psychosis, restlessness, seizures, vertigo

Cardiovascular: Edema, heart failure, hypertension

Eyes, Ears, Nose, And Throat: Cataracts, exophthalmos, glaucoma, increased ocular pressure

Endocrine: Adrenal insufficiency, Cushing's syndrome, growth suppression in children, hyperglycemia

Gastrointestinal: Anorexia, gastrointestinal bleeding and ulceration, increased appetite, indigestion, intestinal perforation, nausea, pancreatitis, vomiting

Genitourinary: Menstrual irregularities

Musculoskeletal: Avascular necrosis of joints, bone fractures, muscle atrophy or weakness, myalgia, osteoporosis

Skin: Acne; diaphoresis; ecchymosis; flushing; petechiae; striae; thin, fragile skin

Other: Delayed wound healing, hypernatre-mia, hypokalemia, negative nitrogen balance

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Nursing Considerations for Generic Drugs

•Administer once-daily doses of prednisone in the morning to match body's normal cortisol secretion schedule.

• Because prednisone can produce many adverse reactions, assess regularly for signs and symptoms of such reactions as heart failure and hypertension. Also monitor fluid intake and output and daily weight.

• Monitor growth pattern in children. Prednisone may retard bone growth.

• Be aware that prolonged use of prednisone may cause hypothalamic-pituitary-adrenal suppression.

WARNING Withdraw prednisone gradually, as ordered, if therapy lasts longer than 2 weeks. Stopping abruptly may cause acute adrenal insufficiency and, possibly, death.

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