Procardia (Nifedipine)
Class and Category of Drug
Before you buy Procardia (Nifedipine) online, read common information about the medication.
Chemical class: Dihydropyridine derivative
Therapeutic class: Antianginal, antihypertensive
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Procardia (Nifedipine) online , you must read how it works.
To manage angina
Capsules (Adalat, Apo-Nifed, Novo-nifedin, Nu-Nifed, Procardia)
Adults. Initial: 10 mg t.i.d., increased oveк 1 to 2 wk as needed. Maintenance: 10 to 20 mg t.i.d. Maximum: 180 mg daily, 30 mg/dose.
E.R. Tablets (Adalat XL, Procardia XL)
Adults. Initial: 30 to 60 mg daily, increase or decreased over 7 to 14 days based on patient response. Maximum: 90 mg daily.
To manage hypertension
E.R. Tablets (Adalat CC)
Adults. Initial: 30 mg daily. Maintenance: 30 to 60 mg daily, increased or decrease over 7 to 14 days based on patient response. Maximum: 90 mg daily.
E.R.Tablets (Adalat PA)
Adults. Initial: 10 to 20 mg b.i.d., increased every 3 wk based on patient response. Maintenance: 20 mg b.i.d. Maximum: 80 mg daily.
E.R. Tablets (Adalat XL)
Adults. Initial: 30 to 60 mg daily, increased or decreased over 7 to 14 days based on patient response. Maintenance: 60 to 90 mg daily. Maximum: 120 mg daily.
E.R.Tablets (Procardia XL)
Adults. 30 to 60 mg daily, increased or decreased over 7 to 14 days based on patient response. Maximum: 120 mg daily.
Dosage Adjustment
Dosage may be reduced for elderly patients and those with heart failure or impaired hepatic or renal function.
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Contraindications of Drug
Read contraindications if you want cheap Procardia (Nifedipine) online.
Hypersensitivity to a calcium channel blocker, second- or third-degree atrioventricular block without artificial pacemaker, sick sinus syndrome
Generic Drug Interactions
Drugs
anesthetics (hydrocarbon inhalation): Possibly hypotension
antiviral drugs, cimetidine, dalfopristin, diltiazem, erythromycin, fluconazole, itraconazole, ketoconazole, nefazodone, other antihypertensives, prazocin, quinupristin, timolol, valproic acid, verapamil: Increased risk of hypotension
benazepril: Possibly increased heart rate and hypotensive effect
beta blockers: Increased risk of profound hypotension, heart failure, and worsening of angina
calcium supplements: Possibly interference with action of nifedipine carbamazepine, nonsteroidal anti-inflammatory drugs (NSAIDs), phenobarbitone, phenytoin, rifampin, rifapentine, St. John's wort, sympathomimetics: Possibly decreased therapeutic effects of nifedipine
digoxin: Transiently increased blood digoxin level, increased risk of digitalis toxicity disopyramide, flecainide: Increased risk of bradycardia, conduction defects, and heart failure
doxazocin: Decreased doxazocin effectiveness; increased nifedipine effectiveness estrogens: Possibly increased fluid retention and decreased nifedipine effects
lithium: Increased risk of neurotoxicity
metformin: Increased metformin absorption and plasma level
tacrolimus: Decreased tacrolimus metabolism
Foods
grapefruit, grapefruit juice: Possibly increased bio availability of nifedipine high-fat meals: Possibly delayed nifedipine absorption
Activities
alcohol use: Additive hypotensive effect
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Drugs Adverse Reactions
Central Nervous System: Anxiety, ataxia, confusion, dizziness, drowsiness, headache, nervousness (possibly extreme), nightmares, paresthesia, psychiatric disturbance, syncope, tremor, weakness
Cardiovascular: Arrhythmias (bradycardia, tachycardia), chest pain, heart failure, hypotension, palpitations, peripheral edema
Eyes, Ears, Nose, And Throat: Altered taste, blurred vision, dry mouth, epistaxis, gingival hyperplasia, nasal congestion, pharyngitis, sinusitis, tinnitus
Endocrine: Gynecomastia, hyperglycemia
Gastrointestinal: Anorexia, constipation, diarrhea, dyspepsia, elevated liver function test results, hepatitis, nausea, vomiting
Genitourinary: Dysuria, nocturia, polyuria, sexual dysfunction, urinary frequency
Hematologic: Anemia, leukopenia, positive Coombs' test, thrombocytopenia
Musculoskeletal: Joint stiffness, muscle cramps
Respiratory: Chest congestion, cough, dyspnea, respiratory tract infection, wheezing
Skin: Dermatitis, diaphoresis, erythema multiforme, flushing, photosensitivity, pruritus, rash, urticaria
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Nursing Considerations for Generic Drugs
• When starting and stopping nifedipine therapy, taper it, as prescribed, over 7 to 14 days.
• For closely monitored hospitalized patient with angina, dosage may be increased 10 mg every 4 to 6 hours to control chest pain.
• Because of drug's negative inotropic effect on some patients, frequently monitor heart rate and rhythm and blood pressure in patients who take a beta blocker or have heart failure or significant left ventricular dysfunction.
• Monitor fluid intake and output and daily weight; fluid retention may lead to heart failure. Also assess for signs of heart failure, such as crackles, dyspnea, jugular vein distention, peripheral edema, and weight gain.
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