Requip (Ropinirole)
Class and Category of Drug
Before you buy Requip (Ropinirole) online, read common information about the medication.
Chemical class: Non-ergot alkaloid dopamine agonist
Therapeutic class: Antidyskinetic
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Requip (Ropinirole) online , you must read how it works.
To treat signs and symptoms of Parkinson's disease
Tablets
Adults. Initial: 0.25 mg t.i.d. Dosage titrated upward every wk according to the following schedule: 0.25 mg t.i.d. in wk 1; 0.5 mg t.i.d. in wk 2; 0.75 mg t.i.d. in wk 3; 1 mg t.i.d. in wk 4. After wk 4, dosage increased by 1.5 mg daily every wk up to 9 mg daily, then by 3 mg/day up to 24 mg daily. Maximum: 24 mg/day.
Extended-Release Tablets
Adults. Initial: 2 mg once daily for 1 to 2 wk, increased, as needed, in increments of 2 mg/day at 1 wk or longer intervals. Maximum: 24 mg/day.
To treat moderate to severe primary restless legs syndrome
Tablets
Adults. Initial: 0.25 mg 1 to 3 hr before bedtime. Dosage increased after 2 days to 0.5 mg and then to 1 mg at the end of the first wk. If needed, dosage further increased in 0.5-mg increments every wk. Maximum: 4 mg daily.
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Contraindications of Drug
Read contraindications if you want cheap Requip (Ropinirole) online.
Hypersensitivity to ropinirole or its components
Generic Drug Interactions
Drugs
carbamazepine, cimetidine, ciprofloxacin, clarithromycin, diltiazem, enoxacin, erythromycin, fluvoxamine, mexiletine, norfloxacin,omeprazole, phenobarbital, phenytoin,rifampin, ritonavir, troleandomycin: Altered drug clearance and increased blood level of ropinirole
chlorprothixene, domperidone, droperidol, haloperidol, metoclopramide, phenothiazines, thiothixene: Possibly decreased effectiveness of ropinirole
CNS depressants: Additive effects
ethinyl estradiol: Possibly reduced clearance of ropinirole
Activities
alcohol use: Additive effects
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Drugs Adverse Reactions
Central Nervous System: Asthenia, confusion, dizziness, falling asleep during activities of daily living, fatigue, hallucinations, headache, hypo-esthesia, malaise, neuralgia, paresthesia, rigors, somnolence, syncope, transient ischemic attack, vertigo
Cardiovascular: Acute coronary syndrome, angina, bradycardia, cardiac failure, chest pain, hypertension, MI, orthostatic hypotension, palpitations, peripheral edema, sick sinus syndrome, tachycardia
Eyes, Ears, Nose, And Throat: Abnormal vision, dry mouth, nasal congestion, nasopharyngitis, rhinitis, toothache
Gastrointestinal: Abdominal pain, constipation, diarrhea, dyspepsia, gastric hemorrhage, gastroenteritis, indigestion, intestinal obstruction, ischemic hepatitis, nausea, pancreatitis, vomiting
Genitourinary: Elevated BUN level, erectile dysfunction, urinary tract infection
Hematologic: Anemia
Musculoskeletal: Arthralgia; arthritis; exacerbation of restless leg syndrome in the early-morning hours; limb pain; muscle cramps, spasms, or stiffness; myalgia; neck pain; osteoarthritis; tendinitis
Respiratory: Asthma, bronchitis, cough, upper respiratory tract infection
Skin: Diaphoresis, flushing, hot flashes, night sweats, rash
Other: Influenza, intense urges to perform certain activities (such as gambling or sex),viral infection, weight loss
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Nursing Considerations for Generic Drugs
WARNING Expect to reassess patient for excessive sedation periodically during therapy. Excessive, acute drowsiness may arise as late as 1 year after starting therapy.
• When ropinirole is given as adjunct to lev-odopa, expect concurrent dosage of levodopa to be gradually decreased as tolerated.
• Expect to stop ropinirole gradually over
7 days, as follows: over first 4 days, reduce from t.i.d to b.i.d.; during last 3 days, reduce to once daily, followed by complete withdrawal of drug.
WARNING Watch for altered mental status during drug withdrawal. Rapid dose reduction may lead to a symptom complex resembling neuroleptic malignant syndrome that includes fever, muscle rigidity, altered level of consciousness, and auto-nomic instability.
• Watch for orthostatic hypotension, especially in patient with early Parkinson's disease. Orthostatic hypotension can occur more than 4 weeks after start of therapy or after a dosage reduction because ropinirole may impair systemic regulation of blood pressure.
• Monitor patient for hallucinations, especially if patient has Parkinson's disease, is elderly, or takes levodopa.
• Monitor patient for worsening of preexisting dyskinesia; ropinirole may potentiate dopaminergic adverse effects of levodopa.
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Ropinirole
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
Proprietary Preparations
Argentina: Requip;
Australia: Repreve;
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