Requip (Ropinirole) - General Health
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Top » Catalog » General Health » Requip (Ropinirole)


Requip (Ropinirole)

$53.81


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Requip (Ropinirole)

Class and Category of Drug

Before you buy Requip (Ropinirole) online, read common information about the medication.

Chemical class: Non-ergot alkaloid dopamine agonist

Therapeutic class: Antidyskinetic

Pregnancy category: C

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Drug Indications and Dosages

Before purchase Requip (Ropinirole) online , you must read how it works.

To treat signs and symptoms of Parkinson's disease

Tablets

Adults. Initial: 0.25 mg t.i.d. Dosage titrated upward every wk according to the following schedule: 0.25 mg t.i.d. in wk 1; 0.5 mg t.i.d. in wk 2; 0.75 mg t.i.d. in wk 3; 1 mg t.i.d. in wk 4. After wk 4, dosage increased by 1.5 mg daily every wk up to 9 mg daily, then by 3 mg/day up to 24 mg daily. Maximum: 24 mg/day.

Extended-Release Tablets

Adults. Initial: 2 mg once daily for 1 to 2 wk, increased, as needed, in increments of 2 mg/day at 1 wk or longer intervals. Maximum: 24 mg/day.

To treat moderate to severe primary restless legs syndrome

Tablets

Adults. Initial: 0.25 mg 1 to 3 hr before bedtime. Dosage increased after 2 days to 0.5 mg and then to 1 mg at the end of the first wk. If needed, dosage further increased in 0.5-mg increments every wk. Maximum: 4 mg daily.

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Contraindications of Drug

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Hypersensitivity to ropinirole or its components

Generic Drug Interactions

Drugs

carbamazepine, cimetidine, ciprofloxacin, clarithromycin, diltiazem, enoxacin, erythromycin, fluvoxamine, mexiletine, norfloxacin,omeprazole, phenobarbital, phenytoin,rifampin, ritonavir, troleandomycin: Altered drug clearance and increased blood level of ropinirole

chlorprothixene, domperidone, droperidol, haloperidol, metoclopramide, phenothiazines, thiothixene: Possibly decreased effectiveness of ropinirole

CNS depressants: Additive effects

ethinyl estradiol: Possibly reduced clearance of ropinirole

Activities

alcohol use: Additive effects

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Drugs Adverse Reactions

Central Nervous System: Asthenia, confusion, dizziness, falling asleep during activities of daily living, fatigue, hallucinations, headache, hypo-esthesia, malaise, neuralgia, paresthesia, rigors, somnolence, syncope, transient ischemic attack, vertigo

Cardiovascular: Acute coronary syndrome, angina, bradycardia, cardiac failure, chest pain, hypertension, MI, orthostatic hypotension, palpitations, peripheral edema, sick sinus syndrome, tachycardia

Eyes, Ears, Nose, And Throat: Abnormal vision, dry mouth, nasal congestion, nasopharyngitis, rhinitis, toothache

Gastrointestinal: Abdominal pain, constipation, diarrhea, dyspepsia, gastric hemorrhage, gastroenteritis, indigestion, intestinal obstruction, ischemic hepatitis, nausea, pancreatitis, vomiting

Genitourinary: Elevated BUN level, erectile dysfunction, urinary tract infection

Hematologic: Anemia

Musculoskeletal: Arthralgia; arthritis; exacerbation of restless leg syndrome in the early-morning hours; limb pain; muscle cramps, spasms, or stiffness; myalgia; neck pain; osteoarthritis; tendinitis

Respiratory: Asthma, bronchitis, cough, upper respiratory tract infection

Skin: Diaphoresis, flushing, hot flashes, night sweats, rash

Other: Influenza, intense urges to perform certain activities (such as gambling or sex),viral infection, weight loss

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Nursing Considerations for Generic Drugs

WARNING Expect to reassess patient for excessive sedation periodically during therapy. Excessive, acute drowsiness may arise as late as 1 year after starting therapy.

• When ropinirole is given as adjunct to lev-odopa, expect concurrent dosage of levodopa to be gradually decreased as tolerated.

• Expect to stop ropinirole gradually over

7 days, as follows: over first 4 days, reduce from t.i.d to b.i.d.; during last 3 days, reduce to once daily, followed by complete withdrawal of drug.

WARNING Watch for altered mental status during drug withdrawal. Rapid dose reduction may lead to a symptom complex resembling neuroleptic malignant syndrome that includes fever, muscle rigidity, altered level of consciousness, and auto-nomic instability.

• Watch for orthostatic hypotension, especially in patient with early Parkinson's disease. Orthostatic hypotension can occur more than 4 weeks after start of therapy or after a dosage reduction because ropinirole may impair systemic regulation of blood pressure.

• Monitor patient for hallucinations, especially if patient has Parkinson's disease, is elderly, or takes levodopa.

• Monitor patient for worsening of preexisting dyskinesia; ropinirole may potentiate dopaminergic adverse effects of levodopa.

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Ropinirole

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International Brand Drug Names

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