Trileptal (Oxcarbazepine)
Class and Category of Drug
Before you buy Trileptal (Oxcarbazepine) online, read common information about the medication.
Chemical class: Tricyclic iminostilbene derivative
Therapeutic class: Anticonvulsant
Pregnancy category: C
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Drug Indications and Dosages
Before purchase Trileptal (Oxcarbazepine) online , you must read how it works.
As adjunct to treat partial seizures
Oral Suspension, Tablets
Adults and adolescents over age 16. Initial: 300 mg b.i.d. Dosage increased by 600 mg/ day every wk. Usual:: 1,200 mg daily. Maximum: 2,400 mg daily. Children ages 4 to 16. Initial: 4 to 5 mg/kg b.i.d. to maximum initial dose of 600 mg daily. Usual:: 900 mg daily for children weighing 20 to 29 kg (44 to 64 lb); 1,200 mg daily for those weighing 29.1 to 39 kg (65 to 86 lb); 1,800 mg daily for those weighing more than 39 kg. Maximum: 1,800 mg daily.
Dosage Adjustment
For patients with creatinine clearance less than 30 ml/min/ 1.73 m2, usual initial dosage reduced by 50%.
As monotherapy to treat partial seizures
Oral Suspension, Tablets
Adults and adolescents over age 16. Initial: 300 mg b.i.d. Dosage increased by 300 mg/ day every 3 days as needed. Usual:: 1,200 mg daily. Maximum: 2,400 mg daily. Children ages 4 to 16. Initial: 4 to 5 mg/kg b.i.d., increased by 5 mg/kg daily every third day to maximum maintenance dosage, as needed. Maximum: 900 mg daily for children weighing 20 to 24.9 kg (44 to 55 lb); 1,200 mg daily for those weighing 25 to 34.9 kg (55 to 77 lb); 1,500 mg daily for those weighing 35 to 49.9 kg (77 to 110 lb); 1,800 mg daily for those weighing 50 to 59.9 kg (110 to 132 lb); 2,100 mg daily for those weighing 60 to 70 kg (132 to 154 lb).
To convert to monotherapy in treating partial seizures
Oral Suspension, Tablets
Adults and adolescents over age 16. Initial: 300 mg b.i.d. Dosage increased by 600 mg daily every wk over 2 to 4 wk, as needed, while dosage of other anticonvulsant is reduced. Usual:: 1,200 mg daily. Maximum: 2,400 mg daily.
Children ages 4 to 16. Initial: 4 to 5 mg/kg b.i.d., increased by 10 mg/kg daily weekly as needed to maximum maintenance dosage while dosage of other anticonvulsant is reduced over 3 to 6 wk. Maximum: 900 mg daily for children weighing 20 to 24.9 kg (44 to 55 lb); 1,200 mg daily for those weighing 25 to 34.9 kg (55 to 77 lb); 1,500 mg daily for those weighing 35 to 49.9 kg (77 to 110 lb); 1,800 mg daily for those weighing 50 to 59.9 kg (110 to 132 lb); 2,100 mg daily for those weighing 60 to 70 kg (132 to 1541b).
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Generic Drug Mechanism of Action
May prevent or halt seizures by closing or blocking sodium channels in neuronal cell membrane. By preventing sodium from entering the cell, oxcarbazepine may slow nerve impulse transmission, thus decreasing the rate at which neurons fire.
Contraindications of Drug
Read contraindications if you want cheap Trileptal (Oxcarbazepine) online.
Hypersensitivity to carbamazepine, oxcarbazepine, or their components
Generic Drug Interactions
Drugs
carbamazepine, phenobarbital, phenytoin, valproic acid: Decreased blood oxcarbazepine level, possibly increased blood levels of phenobarbital and phenytoin felodipine, verapamil: Decreased blood levels of these drugs
oral contraceptives: Decreased effectiveness
Activities
alcohol use: Possibly additive CNS depressant effects
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Drugs Adverse Reactions
Central Nervous System: Abnormal gait, ataxia, dizziness, fatigue, fever, headache, somnolence, suicidal ideation, tremor
Eyes, Ears, Nose, And Throat: Abnormal vision, diplopia, nystagmus, rhinitis
Gastrointestinal: Abdominal pain, indigestion, nausea, vomiting
Skin: Rash, Stevens-Johnson syndrome, toxic epidermal necrolysis
Other: Anaphylalxis, hyponatremia
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Nursing Considerations for Generic Drugs
• Patient with allergic reaction to carbamazepine may have hypersensitivity to oxcarbazepine.
• Monitor serum sodium level for signs of hyponatremia, especially during first 3 months.
• Monitor therapeutic oxcarbazepine levels during initiation and titration, and expect to adjust dosage accordingly.
• Implement seizure precautions as needed.
• Monitor patient's skin closely. If a reaction develops, notify prescriber at once because
skin reactions caused by oxcarbazepine may be serious or life-threatening. WARNING Watch closely for evidence of multi-organ hypersensitivity, such as fever, rash, organ dysfunction, lymphadenopa-thy, hepatitis, liver function abnormalities, hematologic abnormalities, pruritus, nephritis, oliguria, hepatorenal syndrome, arthralgia, and asthenia. If suspected, notify prescriber and expect to stop drug. Provide supportive care, as prescribed.
• Monitor patient closely for evidence of suicidal thinking or behavior, especially when therapy starts or dosage changes.
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Oxcarbazepine
Preparations
International Brand Drug Names
The information about drugs (tablets, pills, capsules, creams, solution, nasal spray, inhaler) around the world.
Proprietary Preparations
Argentina: Atoxecar; Aurene; Oxca; Oxcazen; Rupox; Trileptal;
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